Treatment of Functional Dyspepsia with Liver-stomach Disharmony by Chaihu Shugan Power based on the theory of "brain-gut axis"
DOI:
https://doi.org/10.53469/jcmp.2024.06(11).29Keywords:
Brain-gut axis, Functional dyspepsia, Brain-gut interaction, Liver and stomach disharmony, Chaihu Shugan PowerAbstract
Functional dyspepsia (FD) is a common digestive disorder. The brain-gut axis (BGA) is a bidirectional regulatory channel between the brain and the gastrointestinal tract. "Brain-gut interaction" is the core of FD pathogenesis, which echoes the theory of liver-spleen. Traditional Chinese medicine has an improve effect on BGA, by regulating the liver qi, strengthening the spleen and stomach, the internal organs and qi are reached. The functional activities of the spleen manifesting in normal transformation and transportation, and Shui Gu subtlety can be digested and transmitted. At the same time, the five internal organs are unimpeded, the qi and blood are harmonized, the heart and veins are smooth, and the emotions are also relaxed. Chaihu Shugan Power is an effective prescription for the treatment of FD with liver and stomach disharmony. Based on the BGA theory, this paper summarizes the clinical evidence-based medicine evidence and action targets of Chaihu Shugan Powder in regulating "brain-gut interaction", and provides a scientific basis for its clinical application.
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