The Law and Academic Thought of Medicine for Treating Disintegrating Leakage in the “Women’s Grand Prescription” based on Data Mining

Authors

  • Mingliang Wang Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Mengru Lei Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China
  • Xiaomao Liu Yulin Hospital of Traditional Chinese Medicine Affiliated to Shaanxi University of Chinese Medicine, Yulin 719051, Shaanxi, China

DOI:

https://doi.org/10.53469/jcmp.2025.07(03).14

Keywords:

Prescription for Women’s Daquan, Caving Leakage, Data mining, Medication rules

Abstract

Objective: To explore the medication rules and academic thoughts of treating disintegrating leakage in “Women’s Grand Prescription”. Methods: Firstly, the drugs for the treatment of leaky disintegration were summarized in the Prescription for Women’s Daquan, and then the characteristics of the drugs such as frequency of use, efficacy, sex, taste and normalization were summarized through the TCM inheritance auxiliary platform (V2.5), and the rules of their formulation were analyzed, and finally the core prescription of drugs was generated. Results: A total of 51 prescriptions and 94 flavors of Chinese medicine were sorted out by collecting the “Good Prescription for Women’s Daquan”. The Chinese medicine with high frequency of use (frequency ≥6 times) was Angelica sinensis, ligusticum Chuanxiong and mugwort leaf, with a total of 16 flavors; The four kinds of drugs of these 16 flavors were mainly warm, cold and ping. The five flavors are more common as Gan, xin and bitter; The liver, spleen and kidney are the main; The efficacy is mainly to tonifying deficiency, hemostasis, warming Li, astringent solid astringent medicine; Among them, 13 pairs of drug combinations (frequency ≥6 times), and 3 pairs of new drug pairs and 3 pairs of new core prescription were obtained by constructing drug relationship network diagram of the core combination. It can be seen that Mr. Chen Ziming achieved the purpose of regulating and replenishing chong Ren and rebuilding menstrual cycle by soothing the liver and strengthening the spleen and the kidney when diagnosing and treating disintegrating hemorrhage.

References

Lin Zheng,Xinrui Yan,Mingming Yue. Research on application rules of acupuncture and moxibution in the treatment of disintegrating leakage acupoint meridians based on Data mining [J]. World Science and Technology-Modernization of Traditional Chinese Medicine,2017,19(07):1219-1223.

Juan Wang.Comparison of curative effect of hysteroscopic electrotomy and hysteroscopic curettage in the treatment of abnormal uterine bleeding [J]. Journal of Practical Medicine,2013,29(14):2307.

Xiaoyan Wang.Characteristics of adverse drug reactions of oral contraceptives [J]. World Latest Medical Information Digest, 2015,15 (21) : 142.

Johnson KC, Aragaki AK, Jackson R, et al.Tissue factor pathway inhibitor, activated protein C resistance, and risk of coronary heart disease due to combine destrogenplusprogestintherapy[J].Arterioscler Thromb Vasc Biol, 2016, 36 (2): 418-424.

Canonico M, Carcaillon L, Plu-Bureau G, et al.Postmenopausal Hormone Therapy and Risk of Stroke: Impact of the Route of Estrogen Administration and Type of Progestogen [J].Stroke, 2016, 47 (7): 17341741.

Jingyu Zhao. Clinical observation of Buyang Yiqi Zhidong Decoction in the treatment of Spleen-kidney Yang deficiency type disintegrating leakage [D]. Harbin: Heilongjiang University of Traditional Chinese Medicine, 2017.

AshrafKhafaga, StevenR. Goldstein. Abnormal Uterine Bleeding [J]. Journal of Obstetrics and Gynecology reported Clinics of North America, 2019.

Baifeng Jiang. Clinical Observation of Yiqi Zhixue Decoction in treating disintegrating leakage [J]. Guangming Chinese Medicine,2021,36(21):3586-3588.

National Pharmacopoeia Commission. 2015 Edition of Pharmacopoeia of the People’s Republic of China (Part 1) [M]. Beijing: China Medical Science and Technology Press, 2015:1750.

Gansheng Zhong.Traditional Chinese Medicine [M]. Beijing: China Traditional Chinese Medicine Press, 2012:454.

Compilation Group of Chinese Herbal Medicine in China. National Compilation of Chinese Herbal Medicine [M]. Beijing: People’s Medical Publishing House, 1975:944.

Guoping Zhao,Shen Dai ,Renshou Chen .The Dictionary of Chinese Materia Medica [M]. Shanghai: Shanghai Science and Technology Press, 2006:3875.

ZongwanXie . Handbook of Common Chinese Medicine Names and Aliases [M]. Beijing: People’s Medical Publishing House, 2001:18.

Editorial Board of Chinese Materia Medica, State Administration of Traditional Chinese Medicine. Chinese Materia Medica (Volume 1) [M]. Shanghai: Shanghai Science and Technology Press, 1999:261-432.

Qiong Chen , Yangshi Zhu , Xuejuan Luo, Tonifying kidney. Clinical observation of Yiqi experience prescription for the treatment of adolescent disintegrating leakage [J]. Journal of Practical Chinese Medicine,2021,37(07):1168-1170.

SunYu, WangYuzhu, MaoLele, etal. Prevalence of abnormal uterine bleeding according to new International Federation of Gynecology and Obstetrics classification in Chinese women of reproductive age: A cross-sectional study. [J]. Medicine, 2018, 97(31): e11457.

XiaoWei Fan, GuoHua Liu , Wen Zhang, et al. Investigation and analysis of disease characteristics of 3000 adolescent outpatients with gynecological diseases [J]. Chinese Journal of Sex Science, 2019,29(04):57-59.

Xiaomei Deng. Observation on the curative effect of Yangyin Zhixue Prescription in the treatment of perimenopausal abnormal uterine bleeding syndrome of liver-kidney Yin deficiency [J]. Inner Mongolia Traditional Chinese Medicine, 2019,39(4):75-76.

Lili Yin . Pharmacological Effects of ginseng and Modern research progress [J]. Clinical Research of Chinese Medicine,2013,5(05):122.

Yuanling Jiang, Nan Feng,Xingyu Shao , et al. Research progress of modern pharmacological action of Astragalus [J]. Journal of Southwest Medical University,2023,46(05):456-460+463.

Jun Gong , MaomeiZhang, Hongwei Liu, et al. Research progress on chemical constituents and pharmacological effects of Artemisia Argyi [J]. Guangzhou Chemical Industry,2018,46(04):10-12.

Bao Xin. Study on the characteristics of wine in Sun Simiao's Traditional Chinese Medicine beauty anti-aging recipe [J]. Chinese Journal of Aesthetic Medicine,2012,21(11):1628-1629.

Wenxia zhang, Quanxi Mei, Xiwen zhong. Around the elbow backup nasty side wine party applications [J]. Journal of traditional Chinese medicine, 2016, 33 (4) 6:923-926.

Downloads

Published

2025-03-28

How to Cite

Wang, M., Lei, M., & Liu, X. (2025). The Law and Academic Thought of Medicine for Treating Disintegrating Leakage in the “Women’s Grand Prescription” based on Data Mining. Journal of Contemporary Medical Practice, 7(3), 71–77. https://doi.org/10.53469/jcmp.2025.07(03).14