Research Progress on the Treatment of Uterine Bleeding by Traditional Chinese Medicine
DOI:
https://doi.org/10.53469/jcmp.2025.07(01).08Keywords:
Uterine bleeding, Traditional Chinese medicine, Treatment, Research progressAbstract
Uterine bleeding refers to heavy vaginal bleeding during a woman's abnormal menstruation, The onset of more acute blood storm is called avalanche, and the disease is slower and less dripping blood is called leakage. Often secondary infection anemia infertility and even shock and other complications, it belongs to severe and urgent gynecology. In this paper, the pathogenesis, etiology, pathogenesis, dialectical treatment and clinical research of caving leakage in recent years were reviewed, with a view to providing references for clinical treatment and basic research.
References
Luo Songping, Tan Yong. Chinese Gynecology [M]. 4th Ed. Beijing: China Traditional Chinese Medicine Press, 2016:84.
Group of Gynecological Endocrinology, Chinese Society of Obstetrics and Gynecology. Guidelines for diagnosis and treatment of abnormal uterine bleeding due to ovulatory dysfunction [J]. Chinese Journal of Obstetrics and Gynecology, 2018, 53(12):7.
Chen Lu, Wang Yan, Feng Tongfu, et al. Application of outpatient hysteroscopy to the etiological classification of PALM-CORIN in 10565 patients with abnormal uterine bleeding [J]. Progress in modern obstetrics and gynecology, 2016, 25 (9): 641-645.
Liu Shuqin, Yin Minmin, Qi Jihong, et al. Clinical study of Yifu Zhixue pill combined with progesterone in the treatment of anovulatory dysfunctional uterine bleeding [J]. Modern Medicine and Clinic, 2019, 34(11): 3399-3403.
Athanatos D, Pados G, Venetis C A, et al. Novasure impedance control system versus microwave endometrial ablation for the treatment of dysfunctional uterine bleeding: a double-blind, randomized controlled trial. [J]. Clinical and experimental obstetrics & gynecology, 2015, 42(3):347-351.
Zong X F. Progress in the pathogenesis of dysfunctional uterine bleeding [J]. China Medical Review, 2011, 15:9-10.
Cui Shuying, Liu Suju, Li Xiaobo. Expression and significance of Bcl-2, bax and P53 in anovulatory dysfunctional uterine bleeding [J]. Chinese Journal of Clinical Research, 2013, 6:567-568.
Xu Yunxia, Xu Jingfeng, Li Weili. Discussion on Xu Zhihua's academic thoughts on treating disintegrating leakage [J]. Journal of Anhui College of Traditional Chinese Medicine, 2012, 31(03):12-14.
Wu Yue, Zeng Meijing, Li Chunxiang, et al. Li Chunxiang's clinical experience in the treatment of disintegrating leakage [J]. Marriage, Parenthood and Health, 2023, 29(08):43-45.
Zhang Li, Huang Suying. Tsai genre treatment of department of gynaecology ren dynasties academic characteristic analysis [J]. Journal of zhejiang university of Chinese medicine, 2015, 33 (7) 6:531-533.
He Fengjie, Zhu Hongli, Li Xiaoning. Study on ultrastructure of endometrial hyperplasia in rats with targeted intervention of Huoxue removing stasis [J]. Jiangsu Chinese Medicine, 2011, 43(05):90-92.
Qin Lili, Liang Peifang. Clinical analysis of combined application of Dain-35 and estron in the treatment of 60 cases of impaired blood in adolescence [J]. Agricultural Reclamation Medicine, 2010, 32(04):326-328.
Li Chunfang, Chang Fengqiu, Qi Bing, et al. Experimental study on the effects of Huangbai Baiwei Powder on the levels of sex hormone and the expression of ER and PR in endometrium of rats with dysfunctional uterine bleeding [J]. Chinese Journal of Pharmacoeconomics, 2014, 9(S1):25-27.
Wei Aiwu. Experimental study on mechanism of action of Gongxuening II Granule on gonadal axis [D]. Tianjin College of Traditional Chinese Medicine, 2002.
Li Chunfang, Qi Bing, Chang Fengqiu, et al. Effect of Huangbai Baiwei Powder on coagulation function in rats with dysfunctional uterine bleeding [J]. Chinese ethnic medicine miscellaneous. Tzu chi, 2016, 22 (9): 46-48.
Wang Ling, Ha Xiaoxian, Qu Caiqin, et al. Experimental study on Gongxuening Ⅰ and Ⅱ Granules [J]. Tianjin Traditional Chinese Medicine, 2002(02):13.
Zhou Yan, He Fengjie, Zhao Xixia. Research progress on the relationship between Bcl-2/Bax and dysfunctional uterine bleeding [J]. Journal of Modern Chinese and Western Integrative Medicine, 2011, 20(05):648-650.
He Fengjie, Li Xiaoning, Shi Shuai. Effect of Xiangmembrane-Zhichangfang on endometrial cell apoptosis and bcl-2 and bax gene expression in anovulatory dysfunctional uterine bleeding rat model [J]. Journal of Soochow University (Medical Journal), 2012, 32(02):207-210.
Gao Xiaoqin. Based on data mining of ancient and modern traditional Chinese medicine treatment of ren drug law [J]. Journal of drug evaluation, 2023, 20 (02): 169-173.
Yang Min, Jiang Miao, Chen Yong, et al. Effect of Paeoniae alba on hemostasis [J]. Chinese Medicine and Clinic, 2017, 8(04):37-38.
Ma Y, Zhang Y G, Shi P, et al. Processed products of angelica sinensis and its effect on the chemical constituents and pharmacological research progress [J]. Chinese journal of traditional Chinese medicine, 2023, 13 (22): 6003-6010.
Yang Yan, Liu Dan, Deng Chunhai, et al. Study on the mechanism of Siwu Decoction combined with Astragalus to improve immunity based on network pharmacology and molecular docking technique [J]. Journal of North Sichuan Medical College, 2019, 38(05):584-589.
Han Xuemei, LAN Jing, Wang Tianping, et al. On the characteristics of treating the syndrome of disintegrating leakage in Women's Grand Prescription [J]. Heilongjiang Chinese Medicine, 2014, 43(06):8-9.
Luo Lina, He Ruoping. He Reping experience in the treatment of ren [J]. Journal of zhejiang university of Chinese medicine, 2023, 47 (10): 1143-1146.
Ding Ning, Xu Shijie, Jiang Xiuxin, et al. Treating blood syndrome of menstrual diseases from the heart [J]. Journal of Traditional Chinese Medicine, 2022, 63(03):284-287.
Zhang Haiying. Ren XuJingSheng treatment experience [J]. Journal of shanxi traditional Chinese medicine, 2023, 33 (10) 6:4-6.
Jia Wei, Wang Cuixia. Cui-xia wang installment treating blood stasis and promoting blood circulation to remove blood stasis ren [J]. Journal of practical internal medicine of traditional Chinese medicine, 2016, 30 (09): 8-9.
Zhou Y. Clinical observation of 60 cases of spleen-kidney qi deficiency syndrome treated by staging differentiation of TCM prescription [J]. Straits Pharmacy, 2011, 23(12):205-206.
Liu Xiaomao. Liu Maolin's experience in treating adolescent calving [J]. Shaanxi Correspondence of Traditional Chinese Medicine, 1998(05):12-13.
He Weihe, Wang Zhiqi, Jiang Mengliang, et al. Experimental study on hemostatic mechanism of Jiao Ai Decoction [J]. World Journal of Integrated Chinese and Western Medicine, 2012, 7(12):1032-1033+1041.
Huang Qun, Liu Chunxiang. Clinical observation of treating 70 cases of adolescent functional uterine bleeding with Jiao Ai Tang [J]. Clinical Research of Chinese Medicine, 2011, 3(10):37-38.
Cao Yiming, Wang Yuechu, Shi Yating, et al. Study on the mechanism of Gubenzhipeng Decoction in treating dysfunctional uterine bleeding based on network pharmacology [J]. World of Chinese Medicine, 2019, 17(07):947-952.
Zhou Meiyun. Clinical observation of Gubenzhigong decoction in treating female spleen-qi deficiency type collapse [J]. Chinese Journal of Rural Health, 2019, 12(15):80+75+77+79.
Jin Xiang, Shi Le, Wang Shanshan, et al. Effect of different extraction parts of Taohong Siwu Decoction on blood pattern of blood deficiency and blood stasis model rats [J]. Journal of Shaanxi College of Traditional Chinese Medicine, 2010, 33(3):68-69.
Zhu Xiufen. Taohong Siwu Decoction for treating 280 cases of disintegrating leakage [J]. Hebei Chinese Medicine, 2008, 30 (6):596.
Liu Xiao-Hong, Liu Chen, Shen Yan, et al. Clinical observation of Duan's Dehumidification Decoction in the treatment of perimenopausal damp-heat type disintegration [J]. Journal of Practical Chinese Medicine, 2022, 38(11):1841-1844.
Huang L Z, Li M F, Chen Y M, et al. Lingnan hemostatic prescription 2 mori soup the clinical curative effect of treatment of spleen and kidney deficiency type ren study [J]. Journal of guangzhou university of Chinese medicine, 2023, 40 (8): 1935-1941.
Bai Xiaojuan, Li Yunbo, Liu Hongmei. Uterine acupuncture treatment of ren experience analysis [J]. Journal of shaanxi university of traditional Chinese medicine, 2022, (3): 19-22.
Wang L M, Liu Sui, Niu X X, et al. Treatment of 40 cases of abnormal uterine bleeding in perimenopausal period of spleen and kidney deficiency type with Jianpi Bushen Zhixue prescription combined with acupuncture and moxibustion [J]. Global Journal of Chinese Medicine, 2019, 15(04):693-695.
Wu Xueling. Comparison of clinical efficacy of Gubenzhitong Decoction combined with acupoint application and simple Western medicine in the treatment of abnormal uterine bleeding [J]. Inner Mongolia medicine, 2022, 9 (3): 113-114.
Yao Y. Observation on the curative effect of acupoint embedding and regulating cycle in the treatment of abnormal uterine bleeding due to ovulation disorder (blood stasis syndrome) [D]. Hunan university of Chinese medicine, 2022.
Xia Wan-Ting, Deng Lin-Wen, Shi Ling, et al. Leonurus injection of ovulation obstructive abnormal uterine bleeding hemostatic efficacy observation [J]. Chinese journal of practical gynecology and obstetrics, 2020, 4 (12): 1196-1199.
Zhuang Bingjie. Compared with western medicine therapy with Chinese medicine therapy for the treatment of ren [J]. The world's latest medical information abstract, 2019, 12 (A0): 151 + 153.
Erken Polati, He Xin, Xin Xiaoyi. Progress in the treatment of menstrual diseases with Traditional Chinese and Western Medicine [J]. Xinjiang Traditional Chinese Medicine, 2019, 42(01):91-94. (in Chinese)
Yuan Chunyan. Clinical analysis of compound levonorgestrel in the treatment of functional uterine bleeding [J]. Chinese Medicine Prescription Drugs, 2017, 15(3):68.
Kriplani A, Kulshrestha V, Agarwal N, et al. Role of tranexamic acid in management of dysfunctional uterine bleeding in comparison with medroxyprogesterone acetate[J]. Journal of Obstetrics and Gynaecology, 2006, 26(7):673-678.
Liu Erfang, Ju Jie. Clinical study of Ziyin Bushen styptic Decoction combined with estrogen in the treatment of impaired blood in adolescence [J]. Journal of Practical Chinese Medicine, 201, 37(04):578-580.
Chen Xiangyan, Sun Yun, Lu Yibin, et al. Kidney fill pure side kidney ren clinical curative effect observation [J]. Chinese journal of traditional Chinese medicine, 2022, 40 (02): 105-107.
Zhou Miaoying. Clinical efficacy and safety of Shugan Qingre Decoction combined with deoxypregnenestradiol in the treatment of abnormal uterine bleeding in childbearing age and non-pregnancy [J]. Clinical rational drug use, 2023 (26): 100-102.
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Copyright (c) 2025 Jiedan Deng, Xiaomao Liu
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