Discussion on Pathogenesis and Treatment of OHSS with TE in Special Parts Based on the Theory of “Prolonged Illness Invading the Collaterals”

Abstract

TE associated with OHSS is a rare but fatal complication, and its thrombus distribution has a significant tendency to head and neck, which is different from conventional venous thromboembolism. The study found that although the formation of OHSS thrombosis was acute attack, its root lay in the basis of “chronic disease” of “kidney essence depletion”. The core pathogenesis was “excessive yang transformation, excessive yin formation” and “liver failure to discharge”, resulting in “deficiency of body fluid and blood stasis”. The final pathological product was ascending along the liver meridian and blocking the neck-skull collaterals. The treatment should be based on “dredging collaterals” as the general principle, combined with tonic deficiency, eliminate evil, and skillfully use of drugs to guide the channel, in order to achieve accurate treatment.