An Exploration of Professor Li Jun’s Experience in Preventing and Treating Hypertension via Integrated Medicinal and Dietary Interventions from the Perspective of Body-Disease Correlation

Abstract

Objective: Based on the theory of body and disease correlation and Professor Li’s clinical experience in the use of medicine and food for the treatment of hypertension. Methods: The medical records of Professor Li Jun’s diagnosis and treatment of hypertension were collected, and 201 valid medical records were selected and imported into the traditional Chinese medicine inheritance computing platform V3.5. The frequency and the properties of herbs in the prescription were analyzed by association rules and k-means clustering algorithm, and the differences of blood pressure indexes before and after treatment were analyzed by SPSS 26.0. Results: Statistical analysis of the prescription frequency and usage patterns of edible-medicinal herbs revealed that the predominant properties were cold and warm, the principal flavors were bitter pungent and sweet, and the primary meridians involved were the liver and spleen meridians. Through association rule mining, five core herb combinations of medicine-food homology were identified; clustering analysis revealed four core food-medicine prescriptions. Statistical analysis showed a significant difference in blood pressure changes before and after treatment. Conclusion: Professor Li, based on the hypertension associated with phlegm and blood stasis pathogenesis, used dietary interventions to regulate the damp-phlegm and blood stasis constitution of patients, improve clinical symptoms of hypertension, and provide a theoretical basis and data support for traditional Chinese medicine diet in the prevention and control of hypertension.