Research Progress on the Correlation Between Gut Microbiota and Acute Pancreatitis

Abstract

The role of intestinal dysbiosis in the occurrence and development of acute pancreatitis (AP) is becoming increasingly clear. Biomarkers such as intestinal microbiota diversity, changes in the abundance of key bacteria, intestinal barrier function markers and their metabolites provide a new perspective for early prediction of the severity of SAP and the assessment of prognosis due to their non-invasive and dynamic monitoring characteristics. This article systematically reviews the relationship between the above indicators and the severity and prognosis of AP, discusses the mechanism, and reviews the clinical application status, challenges and future transformation directions of treatment strategies based on gut microbiota regulation, aiming to provide new ideas for the precise management of AP.