Progress in Clinical and Basic Research of Buzhong Yiqi Decoction in Treating Lung Cancer

Abstract

Lung cancer is the leading cause of cancer-related death in the world, and its hidden onset is a difficult problem in clinical practice. Conventional western medicine treatment, including surgery, chemoradiotherapy, targeted therapy, has achieved a certain effect, but there are obvious side effects, poor compliance, high recurrence rate, affecting the prognosis. Buzhong Yiqi Decoction comes from Li Dongyuan’s “on the Differentiation of Internal and External Injuries”. It has the function of tonifying lung and invigorating spleen and regulating qi and blood. Clinical studies have found that Buzhong Yiqi decoction can promote lung cancer postoperative recovery, adjuvant chemotherapy, combined targeted therapy, reduce adverse reactions, improve cancer-related fatigue, improve patients’ quality of life; Basic studies have shown that Buzhong Yiqi Decoction plays its anti-tumor role by inducing apoptosis of cancer cells, anti-tumor angiogenesis, enhancing immune function and reversing drug resistance. This paper discusses the treatment of lung cancer by Buzhong Yiqi Decoction from three aspects: prescription and syndrome analysis, clinical research and basic research, aiming to further study the new progress of Buzhong Yiqi decoction in the treatment of lung cancer, in order to provide a broader idea for clinical diagnosis and treatment.