Research Progress of Traditional Chinese Medicine in Regulating Intestinal Flora in the Treatment of Liver Injury
DOI:
https://doi.org/10.53469/jcmp.2024.06(07).36Keywords:
Traditional Chinese medicine, Intestinal flora, Liver injury, Liver protectionAbstract
Liver injury can be divided into three types: physical liver injury, viral liver injury and chemical liver injury, and the pathogenesis of each type of liver injury is related to the imbalance of intestinal flora. Traditional Chinese medicine can treat liver injury by improving the structure of microflora, regulating the number of microflora and adjusting the homeostasis of intestinal flora. This article provides a basis for a general review of the mechanism of traditional Chinese medicine in the treatment of liver injury by regulating intestinal flora in recent years.
References
Yu Xiaogang, Xin Erdan, Yang Wenyuan, et al. Research progress on material basis and action mechanism of toxic traditional Chinese medicine [J]. Clinical Journal Of Chinese Medicine, 2022, 14 (20): 141-145.
Li Zhiqi, Fan Qiqi, Chen Meilin, et al. Material basis for liver toxicity of traditional Chinese medicine and research progress on its mechanism [J]. Chinese Traditional and Herbal Drugs, 2021, 52(13):4082-4095.
DENG Xin-yu, MA Xiao. Research progress on the pathogenesis and treatment of liver injury[J]. Pharmacy and Clinics of Chinese Materia Medica, 2022, 13(5):118-123128.
ZHOU Xin, DENG Qingang. Review on the hepatoprotective effect and mechanism of natural products on chemical liver injury [J]. Journal of Guizhou Normal University: Natural Sciences, 2018, 36(5):1-11.
Wang Jing. Study on the mechanism of glycyrrhizic acid mediated by intestinal flora in the treatment of chronic liver injury in rats [D]. Nanjing University of traditional Chinese Medicine, 2019.
Thursby E, Juge N. Introduction to the human gut microbiota. Biochem J. 2017;474(11):1823-1836. Published 2017 May 16.
WU Lin-jing, YU Xue-chun, KE Jia-qun, et al. Research Progress in Treatment of Chemical Liver Injury with Chinese Medicine Based on Metabolomics [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2021, 27(12):202-215.
WANG Saisai,QI Yong. Professor Zhao Xueyin's treatment experience of chronic hepatitis B [J]. Guangxi Journal of Traditional Chinese Medicine, 2022, 45(5):44-46.
Zhang Yiyi, Li Zhenhua, Sun Jian, et al. An Experience Case Report of Liu Xi Xiaoyao Wuling Decoction in Treating Drug-induced Liver Injury [J]. Journal of Practical Traditional Chinese Medicine, 2023, 39(2):418-419.
Guo Zhonghua. One case of severe drug-induced liver injury [J]. Clinical Journal Of Chinese Medicine, 2019, 11(26):53-55.
Nie Shaoping, Cai Hailan. Research Progress in Bioactive Components and Functions of Dendrobium officinale [J]. Food Science, 2012, 33(23):356-361.
Zhang J, Fan J, Luo H, et al. Alleviation of Alcoholic Fatty Liver by Dendrobium officinale Flower Extracts due to Regulation of Gut Microbiota and Short-Chain Fatty Acids in Mice Exposed to Chronic Alcohol. Foods. 2023;12(7):1428. Published 2023 Mar 28.
Lu Manxia, Huang Kelong, Shi Shuyun, et al. Study on the Chemical Constituents of Selaginella involvens Spring and Antibacterial Activity [J]. Natural Product Research and Development, 2009, 21(6):973-975.
Wen Yangmin, Tian Li, Cai Lian, et al. Effects of aqueous extract of Selaginella officinalis on liver protection and intestinal flora in mice with acute alcoholic liver injury [J]. Chinese Traditional Patent Medicine, 2023, 45(6):2016-2022
Li Hailong. Study on the improving effect and mechanism of biotransformation of Tripterygium polysaccharide by lactic acid bacteria on cadmium-induced renal injury in mice [D]. Jilin Agricultural University, 2023.
Liu Shu. Protective effect of polysaccharides from Tripterygium wilfordii on acute alcoholic liver injury and its effect on intestinal flora [D]. Jilin Agricultural University, 2022.
Li Xiang, Li Ji. The Research Progress of the Pharmacological Function of Active Components Extracted from Gancao [J]. Jiangsu Journal of Traditional Chinese Medicine, 2019, 51(5):81-86.
Yang Biqian, Yin Tingmei, Deng Yi, et al. To explore the protective effect of Glycyrrhiza uralensis on drug-induced liver injury based on network pharmacology and intestinal flora [J / OL]. Proprietary Chinese medicine, 1-11 [2024-06-25].
WANG Jing, YUAN Tian-jie, CHEN Le-tian, et al. Total saponins of Glycyrrhiza inflata and its decoction on intestinal flora in rats with liver injury [J]. Chinese Traditional and Herbal Drugs, 2020, 51(1):101-108.
WEI Xiyu, YANG Ting, LIU Houru, et al. Research progress on pharmacological effects of salvianolic acid B [J]. Journal of Pharmaceutical Research,, 2021, 40(11):748-752.
Tian Li, Wan Duanjing, Wen Yangmin. Effect of Salvianolic Acid B on TLR4/MyD88/NF-κB Pathway and Intestinal Bacteria in H22 Tumor-Bearing Mice [J]. Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology, 2023, 25(5):1871-1878.
A La Teng Zhu La, HU Yongfei. Advances in the preparation of alginate oligosaccharides and its biological functions [J]. Chinese Journal of Biotechnology, 2022, 38(1):104-118.
WANG Yutian, MI Jinqiu, QUAN Haowei, et al. Effects of Alginate Oligosaccharides on Liver Injury of Mice Induced by Deoxynivalenol [J]. CHINESE JOURNAL OF ANIMAL NUTRITION,, 2023, 35(10):6748-6758.
LIN Ping-dong, CHEN Li-fei, WU Yun-kun. Preparation, Chemical Structure and Bioactivity of Polysaccharides from Gardenia jasminoides Ellis fruit:A Review [J]. Food Research and Development, 2022, 43(19):218-224.
Fang Shuo. Effect of Gardenia jasminoides polysaccharides on intestinal flora against cholestatic liver injury induced by ANIT and its mechanism [D]. Shanghai University of traditional Chinese Medicine, 2021.
Li Sitong, BIAO Ya-ning, Liu Chen-xu, et al. Protective effect of jiedu Hugan Tongluo recipe on drug-induced liver injury in mice and its effect on intestinal flora and intestinal mucosal barrier [J]. World Science and Technology-Modernization of traditional Chinese Medicine, 2024, 26 (02): 351-359.
HU Wei-wei, BIAO Ya-ning, PENG Xiao-yua, et al. Correlation Between Prevention and Treatment Effect of Jiedu Hugan Formula on APAP-induced Liver Injury and Intestinal Microecology [J]. Journal of Hebei Traditional Chinese Medicine and Pharmacology, 2023, 38(4):5-10.
Wang Manfei. Protective effect and mechanism of YinChen Siling Decoction on intestinal mucosal barrier in rats with alcoholic liver injury [D]. Hunan University of traditional Chinese Medicine, 2023.
LIAO Xiaomei, CHEN Meili, ZHANG Lu, et al. The efficacy and mechanism of Jiawei Xiaozhi Ligan Decoction in intervention of NAFLD based on gut-liver axis [J]. Chinese Journal of Microecology, 2023, 35(8):876-884.
YOU Hongjuan, LI Xiaoyuan, HAN Yafei, et al. efficacy of SI-JUN-ZI decoction in the treatment of alcoholicliver disease and it´s mechanism [J]. Journal of Precision Medicine, 2023, 38(4):334-339344.
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