Exploring the Effects and Molecular Mechanisms of Curcumin on Esophageal Cancer based on Network Pharmacology

Authors

  • Dan Huang Department III of Cadre Ward, Western Theater Command General Hospital, Chengdu 610083, Sichuan, China
  • Jialing Jiang School of Clinical Medicine, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Jieyu Chen Department III of Cadre Ward, Western Theater Command General Hospital, Chengdu 610083, Sichuan, China
  • Xiaodan Hao Department III of Cadre Ward, Western Theater Command General Hospital, Chengdu 610083, Sichuan, China

DOI:

https://doi.org/10.53469/jcmp.2025.07(05).19

Keywords:

Curcumin, Esophageal cancer, Network pharmacology, Molecular mechanisms

Abstract

This study used a network pharmacology approach to analyze the potential role of Curcumin in esophageal squamous cell carcinoma (ESCC). Compared with traditional ESCC treatments, which often have single targets, limited efficacy, and significant side effects. These properties may compensate for the shortcomings of conventional drugs. The study constructed the Curcumin target network and PPI network, systematically analyzing its core targets and related pathways, providing a theoretical foundation for the development of Curcumin as a new drug for the prevention and treatment of ESCC.

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Published

2025-05-29

How to Cite

Huang, D., Jiang, J., Chen, J., & Hao, X. (2025). Exploring the Effects and Molecular Mechanisms of Curcumin on Esophageal Cancer based on Network Pharmacology. Journal of Contemporary Medical Practice, 7(5), 106–109. https://doi.org/10.53469/jcmp.2025.07(05).19