Research Progress of Combination of Chinese and Western Medicine in the Treatment of CKD-MBD

Abstract

Chronic kidney disease mineral matter and abnormal bone metabolism syndrome, which can be manifested as renal bone disease also known as renal osteodystrophy, is one of the multiple complications in patients with chronic kidney disease. It is a special form of abnormal bone mineral metabolism syndrome, mainly caused by renal parenchymal dysfunction or renal parenchymal deficiency leading to bone softening and secondary hyperparathyroidism leading to impaired conversion of vitamin D to its active form, which is accompanied by the development of the disease, which can lead to severe bone damage, which seriously affects the quality of life of patients, greatly increases the risk of fracture, and even endangers their lives. And mineral metabolism disorders can lead to increased cardiovascular morbidity and mortality in CKD patients. With the rising incidence of chronic kidney disease, the incidence of this disease is also increasing, and timely and effective treatment is more important. At present, Western medicine treatment mainly consists of phosphorus binding agents, calcium agents, blood purification and other treatments, with a relatively single target of action, and there is a lack of experimental basis for the selection of drugs for different types of renal bone disease, which makes the selection of clinical drugs difficult. Chinese medicine, on the other hand, is characterized by individualization, multi-targeting and holistic treatment, and a large number of studies have shown that the combination of Chinese and Western medicine has achieved good therapeutic effects in the treatment of this disease. In this paper, the research progress of the combination of Chinese and Western medicine in the treatment of CKD-MBD syndrome is summarized in order to provide more ideas for clinical work.