Research Progress on the Treatment of Knee Osteoarthritis with Duhuo Jisheng Decoction
DOI:
https://doi.org/10.53469/jcmp.2025.07(01).02Keywords:
Duhuo Jisheng Decoction, Arthritis, Knee Joint, Mechanism of Action, Treatment Outcomes, ReviewAbstract
Knee osteoarthritis (KOA) is a chronic degenerative disease characterized by cartilage degeneration, subchondral bone sclerosis, and synovial inflammation in the knee joint. Traditional Chinese medicine has unique advantages in the prevention and treatment of KOA, among which Duhuo Jisheng Decoction has the effects of dispelling rheumatism, relieving arthralgia, nourishing the liver and kidney, and strengthening bones and muscles, which can address both the symptoms and root causes of KOA. The mechanism of action of Duhuo Jisheng Decoction in treating KOA includes inhibiting inflammatory factors and cell pyroptosis, promoting cartilage cell proliferation, and inhibiting cartilage matrix degradation. Clinically, oral administration of Duhuo Jisheng Decoction combined with other medications taken orally or injected into the joint cavity, acupuncture, shock wave therapy, and other therapies have achieved significant therapeutic effects in treating KOA. This article provides a formula explanation of Duhuo Jisheng Decoction and reviews the research progress of Duhuo Jisheng Decoction in treating KOA from two aspects: mechanism of action and clinical efficacy.
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Copyright (c) 2025 Wenxiang Hu, Yang Liu, Bingqian Wang, YinGang Li
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