Exploration on the Mechanism of Wound Healing Effect of the Pair of Muscle-building Jade Red Paste based on the Theory of "Simmering Pus and Long Meat"
DOI:
https://doi.org/10.53469/jcmp.2024.06(11).45Keywords:
Stewed pus and long meat, Sheng Ji Yu Hong Gao, Chronic wounds, Mechanism of actioAbstract
A wound refers to the damage and rupture of the human skin and mucosal surface caused by external forces such as collision, cutting, tearing, and burns. Wound healing refers to a series of pathological and physiological processes in which local tissue is repaired through regeneration, repair, and remodeling after tissue loss caused by external forces. Currently, wound healing faces problems such as prolonged healing cycles, unbearable pain, and the possibility of scar tissue affecting aesthetics after healing, which seriously affects the quality of life of patients. Shengji Yuhong Gao, as a good medicine for treating chronic wounds, can effectively regulate the levels of growth factors, improve wound microcirculation, and enhance the body's immunity. "Boiling pus and growing flesh" is a traditional Chinese medicine external treatment method that promotes wound healing. Therefore, using the "simmering pus and growing flesh" method to guide the use of Shengji Yuhong Gao has a significant healing effect on wounds.
References
Wang Ke, Chao Shengwu Research progress on mechanisms related to wound healing [J]. Chinese Journal of Injury and Repair (Electronic Edition), 2021,16 (01): 81-84.
Yang Minghao, Meng Sitong, Yu Guoyang, etc Research progress of Paeonia lactiflora in wound healing [C]//China Life Care Association Proceedings of the Academic Symposium on Life Care and Smart Health Care-Application of Humanistic Care Nursing Concept in Clinical Nurse Patient Communication North China University of Science and Technology;, 2024:2.
Olsson M, Järbrink K, Divakar U, Bajpai R, Upton Z, Schmidtchen A, Car J. The humanistic and economic burden of chronic wounds: A systematic review [J]. Wound Repair Regen, 2019, 27(1):114-125.
Chen Lei Study on the effect of Yuhong ointment on diabetes foot [J]. Diabetes New World, 2016,19 (06): 29-30.
Edited by Chen Hongfeng Traditional Chinese Medicine Surgery [M]. Shanghai: Shanghai Science and Technology Press, 2007.
Zhu Jing, Peng Danming Research progress on the treatment of chronic non healing wounds [J]. Practical Clinical Practice of Integrated Traditional Chinese and Western Medicine, 2021, 21 (19): 156-159.
He Xuan, Li Jiehui, Li Hengchang, etc Research progress on the mechanism and application of Tori disinfectant powder in the treatment of chronic wounds [J]. Chinese Journal of Burns and Ulcers, 2024, 36 (01): 5-7.
Feng Xin, Zhou Yongmei, Fang Demin Mechanism study on the intervention effect of traditional Chinese medicine on wound healing [J]. Liaoning Journal of Traditional Chinese Medicine, 2015, 42 (08): 1498-1501.
Guo Dongjie, Chen Yu, Li Bin, etc Clinical application and rational thinking of the theory of "simmering pus and growing flesh" [J]. Chinese Journal of Traditional Chinese Medicine, 2017, 32 (11): 4812-4814.
Yang Jianhua, Zhu Yongkang Rethinking the method of steaming pus and moistening meat in traditional Chinese medicine surgery [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 33 (01): 265-267.
Liu Man, Zhang Kaiwei Clinical observation on using Shixiang ointment to promote the repair of chronic difficult to heal wounds based on the concept of "simmering pus and growing flesh" [J]. Journal of Practical Traditional Chinese Medicine, 2024, 40 (03): 423-425.
Yi Jun, Xu Laibin, Wang Wanchun Research progress on clinical application of Shengji Yuhong ointment in chronic skin ulcers [J]. Journal of Jiangxi University of Traditional Chinese Medicine, 2021, 33 (03): 117-120.
Yang Zhenxu, Wang Xiaohan, Han Chaoran, etc Clinical research progress of Shengji Yuhong Gao in the past 5 years [J]. Clinical Research in Traditional Chinese Medicine, 2021,13 (05): 139-142.
Tan Xueyan, Zhou Manman, Wang Haibo A review of research on light powder herbal medicine [C]//Professional Committee on Pharmaceutical History of the Chinese Pharmaceutical Association Proceedings of the 19th National Symposium on Pharmaceutical History and Materia Medica and the 2017 Annual Meeting of the Pharmaceutical History Professional Committee of the Jiangsu Pharmaceutical Association Liaoning University of Traditional Chinese Medicine;, 2017:4.
Qiu Heng, Wang Qi Risk assessment of clinical application of light powder of traditional Chinese medicine [J]. Chinese Journal of Traditional Chinese Medicine, 2015, 40 (14): 2706-2710.
Liu Junqiang, Zhang Mingqin, Han Qingke Application of Improved Shengji Yuhong Ointment in Proctology [C]//Chinese Society of Traditional Chinese Medicine Anorectal Branch Collection of Diagnosis and Treatment of Colorectal Diseases in China Department of Colorectal Medicine, Tianjin Road Community Service Center, Henan Province;, 2014:2.
Huang Honghong, Qin Rihong, Liu Xianfu Chemical composition analysis and pharmacological effects exploration of traditional Chinese medicine Angelica sinensis [J]. World Latest Medical Information Digest, 2019, 19 (58): 127+153.
Wen Lihui, Feng Jiangxue, Chen Xueqing, etc The intervention effect of Mao Shi Lei Huo moxibustion combined with Qu Du Xiao Zhong Tang fumigation and washing on postoperative pain, edema, and wound healing of mixed hemorrhoids with damp heat injection [J]. Hebei Traditional Chinese Medicine, 2022, 44 (12): 1973-1978.
Yin Shaoping, Xu Zeyu, Min Wen, etc Application and Reflection on External Application of Traditional Chinese Medicine Preparations in the Treatment of Chronic Wounds [J]. Journal of Nanjing University of Traditional Chinese Medicine, 2020, 36 (05): 690-695.
Patil K, Bellner L, Cullaro G, Gotlinger KH, Dunn MW, Schwartzman ML. Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury. Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3379-3386.
Alcaraz MJ, Fernández P, Guillén MI. Anti- inflammatory actions of the heme oxygenase-1 pathway [J]. Curr Pharm Des, 2003, 9(30):2541-2551.
Yan Tingting, Xiong Meng, Zhou Yong, etc Repairing wound injuries with Shengji Yuhong collagen sponge [J]. Chinese Journal of Tissue Engineering Research and Clinical Rehabilitation, 2011, 15 (29): 5367-5370.
Li G, Ko CN, Li D, Yang C, Wang W, Yang GJ, Di Primo C, Wong VKW, Xiang Y, Lin L, Ma DL, Leung CH. A small molecule HIF-1α stabilizer that accelerates diabetic wound healing [J]. Nat Commun, 2021, 12(1):3363.
Shams F, Moravvej H, Hosseinzadeh S, Mostafavi E, Bayat H, Kazemi B, Bandehpour M, Rostami E, Rahimpour A, Moosavian H. Overexpression of VEGF in dermal fibroblast cells accelerates the angiogenesis and wound healing function: in vitro and in vivo studies [J]. Sci Rep, 2022, 12(1):18529.
Zhao Xiaole, Liang Yong, Wang Wei, etc Clinical application progress of Shengji Yuhong ointment in the treatment of chronic wounds [J]. Chinese Journal of Traditional Chinese Medicine Information, 2023, 30 (02): 170-172.
Cheng H, Huang H, Guo Z, Chang Y, Li Z. Role of prostaglandin E2 in tissue repair and regeneration [J]. Theranostics, 2021, 11(18):8836-8854.
Dong Xiaopeng, Wang Lijuan, Yi Hua, etc Experimental study on the analgesic and anti-inflammatory effects of Shengji Yuhong ointment [J]. Journal of Gansu University of Traditional Chinese Medicine, 2011, 28 (01): 10-12.
Zhang Jianping, Wang Wei, Shi Yuhong, etc Based on AGEs RAGE/NF-κ B signal pathway, explore the mechanism of Shengji Yuhong ointment in promoting wound healing in diabetes foot ulcer model rats [J]. Journal of Gansu University of Traditional Chinese Medicine, 2024, 41 (05): 1-9.
Shi Yuhong, Wang Xin, Zhang Jianping, etc Based on network pharmacology, the mechanism of Jiyuhong ointment in treating diabetes ulcer [J]. Chinese Journal of Burns and Ulcers, 2023, 35 (03): 178-184.
Yao Chang, Sun Haijian, Yao Yonghui, etc Experimental study on the promotion of granulation tissue growth in mechanical wounds by Shengji Yuhong gelatin sponge [J]. Journal of Medical Research, 2009, 38 (05): 62-65+139.
Gao Weiwei, Yao Chang Clinical observation on the treatment of 32 cases of chronic lower limb ulcers with Shengji Yuhong gelatin sponge [J]. Jiangsu Traditional Chinese Medicine, 2010, 42 (03): 46-47.
Xu Yanlei, Yao Chang Research progress on the mechanism of action and clinical application of Shengji Yuhong Gao [J]. Western Traditional Chinese Medicine, 2016,29 (09): 134-139.
Zhao Chunlin, Wang Lijuan, Dong Xiaopeng, etc The effect of Shengji Yuhong ointment on the immune function of mice with deep second degree burns [J]. Shi Zhen Traditional Chinese Medicine, 2013, 24 (04): 1025-1026.
Yang Xiaoxia, Gao Weiwei, Yao Chang, etc The effect and mechanism of Shengji Yuhong Gao collagen sponge on wound collagen shaping [J]. Shandong Pharmaceutical, 2011, 51 (31): 10-12.
Gardeazabal L, Izeta A. Elastin and collagen fibres in cutaneous wound healing. Exp Dermatol. 2024 Mar;33(3):e15052.
Gao Peng Determination of hydroxyproline in Yuhong Shengji gel by RP-HPLC [J]. Liaoning Journal of Traditional Chinese Medicine, 2012, 39 (09): 1819-1820.
Yao Z, Niu J, Cheng B. Prevalence of Chronic Skin Wounds and Their Risk Factors in an Inpatient Hospital Setting in Northern China [J]. Adv Skin Wound Care, 2020, 33(9):1-10.
Zhao Xiaole, Liang Yong, Wang Wei, etc Clinical application progress of Shengji Yuhong ointment in the treatment of chronic wounds [J]. Chinese Journal of Traditional Chinese Medicine Information, 2023, 30 (02): 170-172.
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