Detoxification and Dispersion Method Intervenes Neurofibrillary Tangles in the Treatment of Diabetic AD
DOI:
https://doi.org/10.53469/jcmp.2024.06(11).14Keywords:
Detoxification and Dispersion Method, Alzheimer's disease, Diabetes mellitus, Toxic damage to the brain collateralsAbstract
Neurofibrillary tangles (NFTs) is one of the pathological manifestations of diabetic encephalopathy that can irreversibly develop into AD. Detoxification and Dispersion Method may play an important role in preventing NFTs, preventing or reversing its formation, and delaying neuronal damage. Based on the theory of "internal knot of toxin and blood stasis" and the basic treatment of "Detoxification and Dispersion Method", this paper tries to explore the Detoxification and Dispersion Method for targeted intervention of neurofibrillary tangle, weaken the neurotoxic damage caused by inflammatory reaction, and protect the normal physiological function of neurons and nerve cells from the identity of "junction of toxin and blood stasis - neurofibrillary tangle" and "clearance of blood brain barrier". This study provides new ideas and methods for the prevention and treatment of diabetic encephalopathy, and provides methodological reference and scientific basis for enriching and developing the theory of "detoxing Sanjie" and "detoxing and stasis internal knot" in traditional Chinese medicine.
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