Progress of “Yiqi and Spleen Enhancement Method” in the Treatment of Colorectal Cancer based on Intestinal Flora
DOI:
https://doi.org/10.53469/jcmp.2024.06(09).25Keywords:
Intestinal flora, Colorectal cancer, Yi qi, Spleen strengtheningAbstract
The intestinal microbiota is located close to the colorectal epithelium and consists of a large microbiota that interacts with host cells to regulate many physiological processes such as energy harvesting, metabolism and immune responses [1]. It corresponds to the functions of the “spleen” in Chinese medicine, which is responsible for the transportation of water and grains and the resistance to evil. The balance of intestinal flora directly reflects the functional status of the “spleen” in TCM. Sequencing studies have revealed the microbial composition and ecological changes in colorectal cancer (CRC) patients, and functional animal model studies have clarified the role of several bacteria in colorectal carcinogenesis, including Clostridium nucleatum, Escherichia coli, and Pseudomonas fragilis strains, which are closely related to CRC [2]. Based on this, this paper reviews the research progress on the mechanism of intestinal flora affecting CRC and the intervention of intestinal flora against CRC by Yiqi and Spleen Method, which provides ideas and references for the prevention of colorectal cancer by traditional Chinese medicine.
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