Visualization Analysis of Shenkang Injection based on CiteSpace Study

Authors

  • Qian Yang Guizhou University of Traditional Chinese Medicine, Guiyang 550002, Guizhou
  • Lian Bi The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang 550003, Guizhou

DOI:

https://doi.org/10.53469/jcmp.2024.06(06).04

Keywords:

Shenkang injection, Chronic kidney disease, CiteSpace, Visual analysis

Abstract

Objective: To explore the current research status and trend of Shenkang injection in the treatment of chronic kidney disease (CKD). Methods: By using CiteSpace6.2.R6 software, we could visually analyze the literature on Shenkang injection in the treatment of chronic kidney disease on CNKI, such as the number of documents issued, authors, institutions, keywords, and emergent word system, in order to better understand the latest research progress in this field. Results: A total of 827 relevant articles were retrieved through analysis and screening, and 663 articles were finally included after screening according to the inclusion and exclusion criteria. Through the systematic analysis, it is concluded that the number of documents issued by relevant research in this research field generally presents a good upward trend, and forms a cooperative team of authors with different numbers of members. According to the author of the document, the top three are Yunhong Wang, Yujie Hao, Yanying Lv, Sudong Tong and so on. According to the number of documents issued, the top three were Qian'an People's Hospital of Hebei Province, Beijing University of Chinese Medicine and Hebei Medical University. After analysis, 342 keywords, 8 keyword clusters, and 14 emergent words were obtained. Through the analysis of emergent words, it is concluded that "renal function", "renal failure", "adverse reactions", "alprostadil", "extracellular matrix" and "therapeutic effect" have become the research hotspots of everyone in the past 5 years. Conclusion: The research hotspots of Shenkang injection mainly focus on improving renal function, clinical therapeutic effect, adverse drug reactions and integrated traditional Chinese and western medicine. Shenkang injection has a good development trend in the treatment of chronic kidney disease, but the cooperation and sharing between different institutions need to be strengthened.

References

Zou J J, Zhou X T, Chen Y K, et al. A review on the efficacy and mechanism of action of Shenkang injection against chronic kidney disease. Biomed Pharmacother, 2020, 132:110833.

Tianmeng Cui, Gengzhen Huang, Yingying Zhang, et al. Mechanism of Shenkang Injection Regulating TGF-β Type I Receptor/Smad Pathway to Inhibit Renal Fibrosis [J]. World Science and Technology - Modernization of Traditional Chinese Medicine, 2023, 25 (10): 3355-3363.

Yajing Ji.Clinical value of alprostadil combined with Shenkang injection in the treatment of diabetic chronic kidney disease [J]. China Practical Medicine, 2021, 16 (18): 134-136. DOI:10.14163/j.cnki.11-5547/r. 2021.18.048.

Tianyu Qin. Effect and mechanism of Shenkang injection on chronic kidney disease and renal fibrosis [D]. Beijing University of Chinese Medicine, 2020. DOI:10.26973/d.cnki.gbjzu.2020.000359.

Jingjing Cai. Effect of Shenkang injection on microinflammatory response and renal blood flow in patients with diabetic nephropathy [J]. Chinese Medical Innovation, 2021, 18 (17): 92-96.

Fang Dou, Yi Ding, Minna Yao, et al. Effect of emodin on TGF-β1-induced fibrosis factor in HK-2 cells by activating autophagy [J]. Chinese Pharmacology Bulletin, 2018, 34 (11): 1555-1559.

Ruxi Yang, Qian Xu, QiYang, et al. Effect of astragaloside IV on Toll/MyD88-dependent pathway in mice with renal fibrosis [J]. Chinese Herbal Medicine, 2017, 48 (18): 3775-3782.

Hanjie Jiang, WanLi, Chen Wang, et al. Protective effect of Danshen powder injection on renal fibrosis in rats with unilateral ureteral ligation [J]. Chinese Journal of New Drugs, 2015, 24 (22): 2606-2611 + 2631.

GaoYan, ChenHang, Haihong Jia et al. Effect of safflower yellow pigment on the expression of TGF-β and type I collagen in experimental renal interstitial fibrosis rats [J]. Medical Research and Education, 2009, 26 (03): 11-13.

Yuehua Wang, Yankai Wang, Xiaona Wei, et al. Effect of safflower yellow powder on type III collagen and transforming growth factor-β1 in experimental rats with renal interstitial fibrosis [J]. Hebei Traditional Chinese Medicine, 2008, (08): 879-881 + 897.

TongSun, JiaMeng, FanZhang, et al. To investigate the mechanism of Shenkang injection in the treatment of chronic renal failure based on network pharmacology [J]. China Medicine, 2021, 16 (02): 235-239.

WenyePan, JinShu. Knowledge map analysis of traditional Chinese medicine in the treatment of peptic ulcer [J]. Gansu Science and Technology Horizontal, 2018, 47 (07): 68-71.

Downloads

Published

2024-06-30

How to Cite

Yang, Q., & Bi, L. (2024). Visualization Analysis of Shenkang Injection based on CiteSpace Study. Journal of Contemporary Medical Practice, 6(6), 17–22. https://doi.org/10.53469/jcmp.2024.06(06).04