Advances in the Role and Mechanism of the 14-3-3 Protein Family in Hepatocellular Carcinoma
DOI:
https://doi.org/10.53469/jcmp.2024.06(08).58Keywords:
14-3-3 protein, Liver cancer, Isoforms, Research progressAbstract
The 14-3-3 protein family contains multiple isoforms that are expressed in different tissues and play key roles in cellular physiological functions through binding to related molecules. This article discusses in detail the role of 14-3-3 proteins in the progression of hepatocellular carcinoma, highlights their regulatory role in cell proliferation, migration, invasion, apoptosis, and autophagy, and emphasizes the potential of using 14-3-3 proteins as therapeutic targets in hepatocellular carcinoma. The article provides a comprehensive review of the role of the 14-3-3 protein family in hepatocellular carcinoma and its mechanisms.
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Copyright (c) 2024 Xinya Wen, Kailin Jiao, Zhaoshuang Li, Yue Hao, Jin Zheng
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