Heterogeneity of GFAP Expression in Alzheimer’s Disease: A Perspective from the Vascular-Inflammation Axis

Authors

  • Yichen Chao Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Yongchang Diwu Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China

DOI:

https://doi.org/10.66069/ojspub.27450820

Keywords:

Alzheimer’s disease, Glial fibrillary acidic protein, Blood biomarkers, Astrocytes, Cerebral small vessel disease, East Asian population

Abstract

Based on the “vascular-inflammation axis” analytical framework, this study evaluates the pathophysiological significance of plasma glial fibrillary acidic protein (GFAP) in Alzheimer’s disease (AD). We systematically analyze its expression heterogeneity and clinical interpretive boundaries, specifically comparing late-onset AD (LOAD) and early-onset AD (EOAD).

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Published

2026-08-20

How to Cite

Chao, Y., & Diwu, Y. (2026). Heterogeneity of GFAP Expression in Alzheimer’s Disease: A Perspective from the Vascular-Inflammation Axis. Journal of Contemporary Medical Practice, 8(8), 101–106. https://doi.org/10.66069/ojspub.27450820

Issue

Vol. 8 No. 8 (2026)

Section

Articles

License

Copyright (c) 2026 Yichen Chao, Yongchang Diwu

Creative Commons License

This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.


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