Progress in the Study of Renal Injury Caused by a Novel Coronavirus

Authors

  • Xian Lu Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Genping Lei Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, Shaanxi, China
  • Dong Yang Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Jingxue Bai Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China

DOI:

https://doi.org/10.53469/jcmp.2024.06(08).27

Keywords:

Corona Virus Disease 2019, Chronic kidney disease, Pathogenesis, Cytokine storms

Abstract

Novel Corona Virus Pneumonia (Corona Virus Disease 2019, COVID-19) in December 2019 became an epidemic disease. Chronic kidney disease (CKD) patients are highly sensitive to COVID-19, in-depth study and understanding of the mechanism of action and prevention and treatment strategies of CKD patients infected with novel coronavirus appears to be crucial. This article explored the selected topic by combing the relevant literature, and summarized the susceptibility to COVID-19 and the mechanism of renal involvement in CKD patients; the article shows that COVID-19 mainly enters the cells with ACE2 as the receptor to damage the kidneys directly, but also through cytokine storm, endothelial damage, immune dysregulation and other indirect ways of renal damage.

References

GAO Mengyuan, ZHAO Yongbing, LIU Xi, et al. Clinical characteristics of liver and kidney injuries and correlation with severity and mortality in patients with COVID-19[J]. Journal of Third Military Medical University, 2021, 43(20): 2241-2249.

Le Stang M B, Desenclos J, Flamant M, et al. The Good Treatment, the Bad Virus, and the Ugly Inflammation: Pathophysiology of Kidney Involvement During COVID-19[J]. Front Physiol, 2021, 12: 613019.

MENG Lingdong, LIU Xiaojing, ZHOU Ting. Progress of Chinese Medicine Research on Chronic Kidney Disease[J]. Shanxi Medical Journal, 2017, 46(06): 662-664.

MIN Rui, LIU Jie, DAI Zhe, et al.Advance in clinical study on pathogenesis on COVID-19[J]. Chinese Journal of Nosocomiology, 2020, 30(08): 1171-1176.

XU Gang. Kidney damage and treatment of patients with COVID-19[J]. Chinese Journal of Nephrology,Dialysis & Transplantation, 2020, 29(05): 452-453.

Qu Zhuan;Wang Huiming. Study on the mechanism of kidney damage in the new type of coronavirus pneumonia (COVID-19) [J]. Chinese Journal of Difficult and Complicated Cases, 2021, 20(05): 527-531.

Menon T, Gandhi S, Tariq W, et al. Impact of Chronic Kidney Disease on Severity and Mortality in COVID-19 Patients: A Systematic Review and Meta-analysis[J]. Cureus, 2021, 13(4): e14279.

Juan L, Shuang-Xi L, Li-Fang Z, et al. Management recommendations for patients with chronic kidney disease during the novel coronavirus disease 2019 (COVID-19) epidemic[J]. Chronic Diseases and Translational Medicine, 2020, 6(2).

Han X, Ye Q. Kidney involvement in COVID-19 and its treatments[J]. J Med Virol, 2021, 93(3): 1387-1395.

CHEN Qilin; LI Pin,; LANG Yue, LIANG Shaoshan, et al. Kidney injury in COVID-19[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, 2020, 29(05): 458-463.

ZHANG Lianfeng, ZHANG Jinsong. Investigation on the UV dose required for inactivation of 2019-nCoV[J]. Water & Wastewater Engineering, 2021, 57(S2): 11-17.

Walls A C, Park Y J, Tortorici M A, et al. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein[J]. Cell, 2020, 181(2): 281-292.

YU Che, ZHAO Xue, WANG Rong. New insights based on the role of ACE2 in neococcal pneumonia and its role in the pathogenesis of kidney disease[J]. Clinical Focus, 2020, 35(11): 1053-1056.

Benedetti C, Waldman M, Zaza G, et al. COVID-19 and the Kidneys: An Update. [J]. Frontiers in medicine, 2020, 7.

Bestle D, Heindl M R, Limburg H, et al. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells[J]. Life Sci Alliance, 2020, 3(9).

LIU Qi, XIAO Wei, ZHANG Xu, et al. Research progress of ACE2 in SARS-CoV-2 infection and pathogenesis[J]. Immunological Journal, 2022, 38(05): 451-455.

Coca A, Burballa C, Centellas P F J, et al. Outcomes of COVID-19 Among Hospitalized Patients With Non-dialysis CKD[J]. Frontiers in Medicine, 2020, 7.

WANG Jin-hong, MA Bin, LI Yan-yan. Research on Medication Rules of Prevention and Treatment of COVID-19 with TCM Based on Correlation Coefficient and Association Rule Analysis[J]. Chinese Journal of Library and Information Science for Traditional Chinese Medicine, 2022, 46(01): 1-5.

ZHANG Meng-meng, WU Qi, ZHANG Xin-xue, et al. Syndrome Differentiation-based Treatment of COVID-19 Based on Theory of Wenyilun [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2020, 26(13): 25-31.

Bikdeli B, Madhavan M V, Gupta A, et al. Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research[J]. Thromb Haemost, 2020, 120(7): 1004-1024.

LIU Yuxiang, LI Yanju,; XU Mujuan,, et al. Summary of the Experience of Shenzhen Traditional Chinese Medicine Team Supporting Hubei inT reating COVID-19 in Leishenshan Hospital[J]. Journal of Practical Traditional Chinese Internal Medicine, 2021, 35(01): 83-85.

XU Xu, ZHANG Yin, LI Xin, et al. Analysis of Traditional Chinese Medicine (TCM) Programs for Prevention of Novel Coronavirus Pneumonia (COVID-19) in Various Regions[J]. Chinese Traditional and Herbal Drugs, 2020, 51(04): 866-872.

NIE Wei, ZHENG Caixia, LI Yongsheng, et al. Clinical experience of treating COVID-19 based on syndrome differentiation of three factors[J]. Clinical Journal Of Chinese Medicine, 2021, 13(36): 38-40.

Wei Kai-yue, Mi Yan, Wang Cai-li. Recent advances in the pathogenesis of acute kidney injury caused by COVID-19 [J]. Journal Of Clinical Nephrology, 2022, 22(10): 866-869.

Askari H, Sanadgol N, Azarnezhad A, et al. Kidney diseases and COVID-19 infection: causes and effect, supportive therapeutics and nutritional perspectives[J]. Heliyon, 2021, 7(1): e6008.

YANG Li, ZHAO Zhigang. Changes and Treatments of Leukocytes in Coronavirus Disease 2019(COVID-19) [J]. Herald of Medicine, 2020, 39(05): 615-620.

Jin M, Tong Q. Rhabdomyolysis as Potential Late Complication Associated with COVID-19[J]. Emerg Infect Dis, 2020, 26(7): 1618-1620.

Wu H, Larsen C P, Hernandez-Arroyo C F, et al. AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk Genotype[J]. J Am Soc Nephrol, 2020, 31(8): 1688-1695.

Cao, Y., Cao, P., Chen, H., Kochendorfer, K. M., Trotter, A. B., Galanter, W. L., ... & Iyer, R. K. (2022). Predicting ICU admissions for hospitalized COVID-19 patients with a factor graph-based model. In Multimodal AI in healthcare: A paradigm shift in health intelligence (pp. 245-256). Cham: Springer International Publishing.

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Published

2024-08-21

How to Cite

Lu, X., Lei, G., Yang, D., & Bai, J. (2024). Progress in the Study of Renal Injury Caused by a Novel Coronavirus. Journal of Contemporary Medical Practice, 6(8), 133–136. https://doi.org/10.53469/jcmp.2024.06(08).27