Research Progress on the Mechanism of Action of Acupuncture in the Treatment of Chronic Functional Constipation
DOI:
https://doi.org/10.53469/jcmp.2024.06(08).23Keywords:
Constipation, Functional constipation, Pathogenesis, AcupunctureAbstract
With the acceleration of the pace of life, the increase of social pressure and the change of dietary structure, chronic functional constipation (FC) has gradually become a common disease that plagues people's normal life, among which slow transit constipation (STC) is the most common. Chronic constipation not only induces a series of anorectal diseases, but also leads to insomnia, anxiety and other psychological problems, which increases the risk of cardiovascular and cerebrovascular diseases for the elderly. Although Western medicine treatment can improve symptoms, the prognosis is often poor, while traditional acupuncture is a green treatment that is simple and easy to implement, with definite efficacy and obvious advantages. This article reviews the research progress on the mechanism of acupuncture in the treatment of chronic functional constipation, aiming to provide enlightenment for clinical treatment.
References
WU Xianshu, LIU Yuedong, et al. Pathogenesis and Acupuncture Treatment of Chronic Functional Constipation[J]. Journal of Practical Traditional Chinese Internal Medicin, 2021, 35(5):43-46.
LI Shi-jun, WU Jian-guo, PENG Zhi-yang, et al. Research progress of fecal microbiota transplantation in treatment of chronic functional constipation[J]. Journal of Practical Traditional Chinese Internal Medicine, 2021, 35(5):43-46.
Zhao Y F, Ma X Q, Wang R, et al. Epidemiology of functional constipation and comparison with constipation-predominant irritable bowelsyndrome: the Systematic Investigation of Gastrointestinal Diseases in China (SILC)[J]. Alimentary Pharmacology ＆ Therapeutics, 2011, 34(8):1020-1029.
Yuan Shaolun, Yuan Huan, Zhang Tao, Zhang Chunlei, Wang Zheng, et al.9 cases of severe cardiovascular events caused by constipation in elderly people[J]. Integrated Traditional Chinese and Western Medicine Cardiovascular Disease Electronic Journal, 2017, 5(17):13-14.
Wang Xiaoyuan, Fu Yan, et al. Investigation on Defecation of Elderly Constipated Patients and Its Pyscholgical Factors[J]. junNursing Journal of Chinese People's Liberation Army, 2009, 26(03):29-30.
Wang Yamei, He Yue, Zhang Lizhi, Fu Lixia, et al. Research status of acupuncture and moxibustion and moxibustion in the treatment of functional constipation[J]. World Latest Medicine Information, 2019, 19(82):120.
Selma Royo M. et al. Perinatal environment shapes microbiota colonization and infant growth: impact on host response and intestinal function[J]. Microbiome, 2020, 8(1): 167-167.
YUE Ling, LI Ying; GAO Rui, SHE Tianwei, CHEN Yaoyao, LI Li; ZHENG Hui, et al. Study on Mechanism of Brain Intestinal Interaction in Treating Functional Constipation by Electroacupuncture at Shu-Mu Points Based on BDNF Expression[J]. Chinese Archives of Traditional Chinese Medicine, 2018, 36(10):2438-2441.
Wang Fang, Zhang Yanli, Yao Shukun, Ma Junyu, et al. Analysis of symptoms and intestinal microflora of severe functional constipation patients[J]. Chinese Journal of Difficult and Complicated Cases, 2014, 13(7):707-709713.
Zhang Yan, Li Hongyan, Guo Lingli, Sun Lingjun, et al. Influence of Dahuang (Radix et Rhizoma Rhei) on colonic motility in rats[J]. Journal of Beijing University of Traditional Chinese Medicine, 2010, 33(3):187 -190I0002.
Kakaki M. Gut pacemaker cells: the interstitial cells of Cajal ( ICC) [J].J Smooth Muscle Ｒes, 2003, 395: 137 - 161.
Liu Baohua, Meng Jian, Zhang Lianyang, Tong Weidong, Zhang Shengben, Wang Jianmin, Li Bingcang, et al. Roles of acetylcholine and isoproterenol on slow transit constipation[J]. Journal of Third Military Medical University, 2004, 26(12):1045-1048.
Song Jianting, Kong Lixia, Zhao Shipeng, et al. Research progress on the etiology and pathophysiology of slow transit constipation[J]. Chinese Journal of Difficult and Complicated Cases, 2013, 12(10):812-815.
Schuster Marvin M. Gastrointestinal Dynamics[M].2nd edition. Shanghai: Shanghai Scientific & Technical Publishers, 2003.
Du Lijuan, Tang Xuegui, Wu Zhijiu, Li Min, et al. Expression and Significance of VIP in Colon Tissues of Chronic Constipation Model Rats[J]. The Journal of Medical Theory and Practice, 2011, 24(15):1755-1756.
Chen Lan, Liu Shi, et al. Enteric nervous system and slow transit constipation[J]. International Journal of Digestive Diseases, 2007, 27(3):178-179185.
Tan Li, Tan Zhirou, Huang Xue, Qin Lirong, et al. The expression of different kinds of NOS in the colon of slow transit constipation rats[J]. Chinese Journal of Gastroenterology and Hepatology, 2011, 20(1):64-66.
Song Ya-Fang et al. Electroacupuncture Relieves Irritable Bowel Syndrome by Regulating IL-18 and Gut Microbial Dysbiosis in a Trinitrobenzene Sulfonic Acid-Induced Post-Inflammatory Animal Model. [J]. The American journal of Chinese medicine, 2020, 48(1): 77-90.
Wang Qian, Chen Kanjun, Yu Ansheng, et al. Study on the therapeutic effect and mechanism of acupuncture and moxibustion on irritable bowel syndrome of liver stagnation and spleen deficiency[J]. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2019, 27(07):520-524.
Sun Yiming. Clinical study of acupuncture and moxibustion intervention on functional constipation after stroke based on intestinal flora[D], 2020.
Xu Mingmin. Study on the mechanism of acupuncture improving gastrointestinal transport function in FC mice based on gut microbiota analysis[D], 2020.
Sun Jianhua, Guo Hui, Chen Lu, Wu Xiaoliang, Li Hao, Pei Lixia, Peng Yongjun, Lu Bin, et al. Effect of electroacupuncture at Tianshu (ST 25) on colonic electromyography in Slow transit constipation rats[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2011, 26(9):2077-2079.
He Hongbo, Li Ning, Wang Chengwei, Lv Jianqin, et al. The Effect of Electro-acupuncture in Different Depths on Colonic Transit Time of Patients with Slow Transmit Constipation[J]. Journal of Clinical Acupuncture and Moxibustion, 2011, 27(6):11-13.
Study on the mechanism of EGCs autophagy and PI3K AKT mTOR signaling pathway in improving gastrointestinal transport function in functional constipation mice through stimulation[D]. Chengdu University of Traditional Chinese Medicine, 2021.
Cao Pinrong, Kong Yingli, Luo Yanmei, Huang Wei, Xu Jianhua, Ye Min, et al. Mechanisms of Resistance to PI3K-Akt-mTOR Signaling Pathway Inhibitors[J]. Chinese Pharmaceutical Journal, 2016, 51(4):253-258.
CHEN Jiping, FANG Yafei, LI Tongzhong, LIANG Chao, et al. Effects of Electroacupuncture at Different Points on BDNF and ChAT in Colon of Mice with Functional Constipation[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2021, 28(9):68-72.
Sun Yanhui, Sun Yonghui, Zhao Zhenshuan, Guo Xinyu, Sun Lihong, Liang Yulei, et al. Effects of warming acupuncture on substance-P and vasoactine intrestinal peptide in rats with slow transit constipation[J]. Chinese Journal of Gerontology, 2012, 32(21):4681-4682.
GAO Yanhong, LI Jianmei, SU Mao, LI Yanling, et al. Acupuncture with smoothing liver and regulating qi for post-stroke slow transit constipation and its gastrointestinal hormone level[J]. Chinese Acupuncture & Moxibustion, 2017, 37(02):125-129.
Xin Yu. Clinical Observation and Experimental Study on Acupuncture Treatment for Functional Constipation [D]. Hubei University of Chinese Medicine, 2015.
YUAN Ying-dan, ZHAO Zheng-yu, et al. Study of the Neuroendocrine Mechanism of the Action of Electroacupuncture on Colonic Motility in a Mouse Model of Slow Transit Constipation[J]. Shanghai Journal of Acupuncture and Moxibustion, 2016, 35(11):1358-1361.
Gao Fang, Sheng Hongmei, Zhang Tianning, Wu Shengbing, Cao Jian, Zhou Meiqi, et al. Effect of Acupuncture at Shangjuxu (ST 37) on Number of Colonic Interstitial Cells of Cajal in Mice with Slow Transit Constipation[J]. Journal of Anhui University of Chinese Medicine, 2014, 33(3):66-69.
Sun Jianhua, Guo Hui, Pei Lixia, Peng Yongjun, Lu Bin, Wu Xiaoliang, Li Hao, et al. The Regulation of C-kit and SCF Gene Expression in Colon of Rats with Slow Transit Constipation by Electroacupuncturing Tianshu Acupoint[J]. Journal of Nanjing University of Traditional Chinese Medicine, 2011, 27(1):33-35.
Snaders KM Ordog T Koh SD et al. Development and plasticity of interstitial cells of Cajal [J]. Neurogastroen- terol Motil 1999:11(5):311-338.
Zhang Qiong, Ni Min, Fan Zhimin, et al. Mechanism of Acupuncture Treatment for Functional Constipation[J]. Journal of Clinical Acupuncture and Moxibustion, 2014, 30(11):79-81.
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Copyright (c) 2024 Ying Xia, Yuanyuan Ren, Moran Hei, Ruitong Shang
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