Research Progress of Diabetic Kidney Disease with Traditional Chinese Medicine
DOI:
https://doi.org/10.53469/jcmp.2024.06(08).14Keywords:
Diabetic kidney disease, Category of wasting and thirst disease, Traditional Chinese medicine, SummarizeAbstract
Diabetic kidney disease is not only a common microvascular complication of diabetes, but also diabetes-specific renal damage. With the progress of the disease, it gradually develops into end-stage renal disease (ESRD). DKD showed podocyte loss, glomerular hypertrophy, Mesangial matrix dilation and glomerular basement membrane thickening in the early stage, and nodular glomerulosclerosis, Mesangial vasolysis, inflammation and interstitial fibrosis in the late stage [1-2]. at present, there is no specific treatment plan in western medicine. Clinical practice shows that traditional Chinese medicine has a significant and definite effect on delaying the progression of diabetic renal diseases. This article will summarize from three aspects: etiology and pathogenesis, syndrome differentiation and treatment.
References
Warren AM, Knudsen ST, Cooper ME. Diabetic nephropathy: an insight into molecular mechanisms and emerging therapies. Expert Opin Ther Targets, 2019, 23:579-591.
Kim Y, Park CW. New therapeutic agents in diabetic nephropathy. Korean J Intern Med, 2017, 32:11-25.
Anders HJ, Huber TB, Isermann B, et al. CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease[J]. Nat Rev Nephrol, 2018, 14(6):361-377.
Ruiz ⁃ Ortega M, Rodrigues ⁃ Diez RR, Lavoz C, et al. Special Issue "Diabetic Nephropathy: Diagnosis, Prevention and Treatment"[J]. J Clin Med, 2020, 9(3): 813.
Hou JH, Zhu HX, Zhou ML, et al. Changes in the spectrum of kidney diseases: an analysis of 40, 759 biopsy ⁃ proven cases from 2003 to 2014 in China[J]. Kidney Dis (Basel), 2018, 4(1):10⁃19.
Lu Renhe, Zhao Jinxi, Wang Yue. A Review of the Researches on Diabetic Renal Disease[J]. Journal of Beijing University of Traditional Chinese Medicine, 1994(02):2-6+72.
Tong Xiaolin, Zhou Qiang, Zhao Linhua, et al. Experience on TCM syndrome differentiation and treatment of diabetic nephropathy[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2014, 29(01):144-146.
Endocrinology and Metabolic Diseases Professional Committee of Integrated Traditional Chinese and Western Medicine Physicians Branch of Chinese Medical Doctor Association Guidelines for Diagnosis and Treatment of Diabetic Nephropathy with Combinations of Diseases and Syndromes[J]. Journal of Traditional Chinese Medicine, 2022, 63(02):190-197.
Lu Mingxing; Zhao Mao; Wang Daoping, et al. Exploration on Mechanism of Huangqi Shengmai Powder on Diabetes Based on Network Pharmacology and Molecular Docking[J]. Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology, 2022, 24(09):3449-3464.
Zhang L, Shergis L J, Yang L, et al. Astragalus membranaceus (Huang Qi) as adjunctive therapy for diabetic kidney disease: An updated systematic review and meta-analysis[J]. Journal of Ethnopharmacology, 2019, 239111921.
The National Pharmacopoeia Commission. The Pharmacopoeia of the People's Republic of China (Chinese Pharmacopoeia[M]. Beijing: China Medical Science and Technology Press, 2020.
Zhang Xuan, Jiang Ruibin, Xue Songyan, et al. Analysis of Pharmacodynamic Mechanism of Radix Rehmanniae and its compatibility in the prevention and treatment of microinflammation in diabetic nephropathy [J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2021 minute 30 (35): 3975-3977-3982.
ZHAO Zhongqiu, ZHANG Zhao. Research progress on the mechanism of salvia miltiorrhiza and its effective ingredients in the treatment of diabetic nephropathy [J/OL]. Global Traditional Chinese Medicine: 1-9[2024-07-14].
Guo Jinming, Zhou Feng, Tan Yang, et al. Study on Poria cocos in the treatment of Diabetic Nephropathy based on Network Pharmacology[J]. Chinese Traditional Patent Medicine, 2020, 42(06):1640-1646.
FAN Yaofu, CAO Lin, SUN Hongping et al. Clinical Study of Gegen Qinlian Decoction in Type 2 Diabetes with Non-alcoholic Fatty Liver Disease[J]. Chinese General Practice, 2021, 24(36):4587-4592.
GUO Zhibo, MA Lina, LIU Danyang. Protective effect of Gegen Qinlian decoction on renal tissue of rats with diabetic nephropathy[J]. Translational Medicine Journal, 2022, 11(01):46-49+41.
GU Yue, ZHENG Linlin, GUO Dengzhou. Danggui Buxuetang Inhibits Mitochondrial Fission and Apoptosis of Podocytes in Rat of Diabetic Kidney Disease via AKAP1/Drp1 Signaling Pathway[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2024, 30(15):38-45.
Wu Ruixuan, Cheng Jinguo, Liu Zhanghong, et al. Effect of Shenqi Dihuang decoction on renal function and microinflammation in patients with diabetic nephropathy in stage Ⅳ-V [J]. Liaoning Journal of traditional Chinese Medicine, 2023, 50(06):157-160.
WANG Huiling; LEI Di; ZHAO Siyang; SI Hailong. Experimental study on regulating podocyte autophagy of diabetic nephropathy rats by Shuilu Dihuang capsule through LKB1/AMPK/Sirt1 signaling pathway[J]. Global Traditional Chinese Medicine, 2021, 14(12):2142-2148.
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