Formulation and Evaluation of Dolasetron Orally Disintegrating Tablets

Abstract

The aim of present study is to formulate Dolasetron orally disintegrating tablets by using by direct compression method and evaluating its characteristics. This dosage form is more comfortable for pediatric and geriatric patients. This serves as orally dispersible system because of its convenient nature. Compared with all the excipient drugs the cross povidone shows high activity. Dolasetron along with cross povidone developed more than 95.34% drug release which show highest number of drug released compared to SSG and cross carmellose. The disintegration time is fast for cross povidone compared to others. Dolasetron might have immense effect on Anti-emetic property as per this study.