Research Progress on the Antitumor Mechanisms of Nano-Realgar

Abstract

Realgar is a sulfide mineral realgar of the realgar family, which is widely used in traditional Chinese medicine. In modern clinical research, it has been applied to leukemia and tumor treatments. However, clinical application of realgar is limited due to its insolubility and low bioavailability. This problem may be solved by using realgar nanoparticles which have shown unique advantages. In this paper, the ancient and modern applications of realgar and the preparation method of realgar nanoparticle are summarized. The antitumor mechanisms of realgar nanoparticles in recent years are explored to provide a reference for the in-depth research of realgar in the field of tumor therapy.