Research Progress on the Pathogenesis and Traditional Chinese Medicine Treatment of Alzheimer’s Disease

Abstract

Alzheimer’s disease (AD), the primary causative factor of dementia, is a progressively degenerative neurological disorder that significantly impairs the quality of life in the elderly population and disrupts familial harmony. Concurrent with the intensifying global aging trend, the prevalence of this disease is persistently increasing, thereby imposing an escalating socio-economic burden. This paper systematically reviews the research progress on the pathogenesis of AD. Furthermore, it summarizes the research advancements in the treatment of AD with Traditional Chinese Medicine (TCM), encompassing aspects such as TCM etiology and pathogenesis, compound formulas, single herbs, active constituents, and acupuncture therapy. The limitations of existing studies are analyzed, and future research directions are proposed. This review aims to provide a theoretical foundation for the formulation of clinical prevention and control strategies for AD and for the development of innovative therapeutic agents.