Application of Spectral CT Hemobase Imaging in Renal Perfusion Assessment Before and After Partial Nephrectomy for Renal Carcinoma

Abstract

Objective: To investigate the significant clinical value of spectral CT hemobase imaging in evaluating renal perfusion function before and after partial nephrectomy for renal cell carcinoma. As described in “Research on Renal CT Perfusion Imaging and Its Clinical Application Value”, this technique provides quantitative analysis of renal perfusion values, aiding in prognosis assessment and surgical strategy selection for renal cancer patients. Methods: A total of 70 patients undergoing partial nephrectomy for renal cell carcinoma from June 2024 to June 2025 were randomly divided into a study group (35 cases) and a control group (35 cases). The study group received spectral CT hemobase imaging to improve early diagnostic accuracy, while the control group underwent conventional contrast-enhanced CT. Preoperative and postoperative 7-day changes in iodine-based substance concentration (IC), spectral curve slope (λHU), effective atomic number (Zeff), renal blood flow (RBF), renal blood volume (RBV), and mean transit time (MTT) were compared. Results: The study group showed significantly higher postoperative IC, λHU, Zeff, RBF, and RBV compared to the control group, with significantly lower MTT (P<0.05). Conclusion: Spectral CT hemobase imaging accurately reflects changes in renal parenchymal microcirculation perfusion during partial nephrectomy for renal cell carcinoma. Compared to conventional contrast-enhanced CT, it demonstrates higher sensitivity and quantitative analysis value, which holds important clinical significance for evaluating postoperative renal function and prognosis.