Current Status and Trends of Clinical Research on Traditional Chinese Medicine in Treating Polycystic Ovary Syndrome Infertility

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of childbearing age. It is associated with a high incidence of infertility, complex etiologies, and significant treatment challenges. Traditional Chinese Medicine (TCM) offers unique advantages in regulating endocrine function, improving ovulatory function, and increasing pregnancy rates. This article systematically reviews the current status of clinical research on TCM treatment of PCOS infertility, including the application and efficacy evaluation of TCM, acupuncture, and integrated TCM therapies. The article also explores its mechanisms of action, including modulating hypothalamic-pituitary-ovarian axis function, improving insulin resistance, regulating sex hormone levels, and enhancing follicular development and endometrial receptivity. The article notes that current research still suffers from issues such as low-quality clinical design, inconsistent syndrome differentiation, and insufficient in-depth mechanistic research. Future research should strengthen standardization, promote high-quality clinical trials, deepen multidimensional mechanism exploration, and establish a personalized treatment system integrating TCM and Western medicine. This will enhance the scientific and standardized application of TCM in assisted reproduction and provide better solutions for women’s reproductive health.