Exploring the Approach of Soothing the Liver and Strengthening the Spleen in Preventing and Treating Hashimoto’s Thyroiditis from the Perspective of Gut Microbiota Dysbiosis

Abstract

Hashimoto’s thyroiditis is a significant immune disorder in modern times, and liver-stomach disharmony is a key pathogenesis in Traditional Chinese Medicine (TCM). Recent studies have found that gut microbiota dysbiosis is correlated with the onset of Hashimoto’s thyroiditis, while the functional characteristics of the TCM “liver” and “spleen” share many similarities with those of gut microbiota. Research indicates that the essence of liver depression and spleen deficiency may be associated with gut microbiota dysbiosis. Clinically, the approach of soothing the liver and strengthening the spleen not only effectively alleviates symptoms of Hashimoto’s thyroiditis but also regulates gut microbiota function. This paper aims to explore the mechanism of soothing the liver and strengthening the spleen in treating Hashimoto’s thyroiditis from the perspective of gut microbiota dysbiosis, with the goal of providing new insights and evidence for its clinical prevention and treatment.