Research Progress of Shaofu Zhuyu Decoction in the Treatment of Male Diseases
DOI:
https://doi.org/10.53469/jcmp.2024.06(06).21Keywords:
Shaofu Zhuyu Decotion, Prostate, Epididymitis, VC, EDAbstract
The effect of Shaofu Zhuyu Decotion is to promote blood circulation and remove blood stasis, warm menstruation, reduce swelling and relieve pain. Its main pathogenesis is cold coagulation and blood stasis. In the systematic collection and analysis of relevant literature in recent years, it has been found that it is widely used in the clinical and experimental research of male diseases, such as chronic prostatitis, epididymitis, prostate hyperplasia, erectile dysfunction, varicocele and infertility, etc. Especially for patients with prostatitis, experimental and clinical research data table, it has a significant curative effect. In the treatment of epididymitis, erectile dysfunction, varicose veins and infertility, there are also studies that it has a positive effect, but there are few relevant reports and more research is needed; the relevant content is summarized as follows.
References
LIU Xiao-miao; ZHANG Jing. General Situation of Five "Kinds of Stasis-Expelling Decoction" in Treating Gynecological Diseases in Correction of Errors in Medical Works[J]. Henan Traditional Chinese Medicine, 2020, 40 (08): 1292-1296.
HONG Jinni, LIN Datao, CHEN Ziying, et al. Effect of Shaofu Zhuyu Decoction on NLRP3 inflammatorome of salpingitis infertility rats[J]. Drug Evaluation Research, 2022, 45 (12): 2486-2493.
LU Ying, WU Tong, WU Jia-wen. Modified Shaofu Zhuyu Decoction inhibits TLR4/TRIF/IRF3 signaling pathway and improves inflammatory microenvironment in rats with endometriosis[J/OL]. Progress of Anatomical Sciences, 2023, 29(05):483-486.
FU Ze-mei, LI Li-juan, WANG Ai-li. Effect of Modified Shaofu Zhuyutang on Pelvic Inflammatory Disease-chronic Pelvic Pain with Cold Damp Stagnation Syndrome[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2018, 24 (10): 200-205.
ZHANG Yu-kun, XIAO Hong-bin, NIU Wen-ying. Effects of Shaofu Zhuyu Decoction on Hemorheology and platelet function in rats with Qi deficiency and blood stasis[J]. Lishizhen Medicine and Materia Medica Research, 2021, 32 (09): 2078-2080.
LI Feng-jin, NIU Wen-ying, LIU Xin-xin, et al. Effect and Mechanism of Shaofu Zhuyutang on Endothelial Injury of Rats with Cold Coagulation and Blood Stasis Syndrome Based on Nrf2/ARE Signaling Pathway[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2021, 27 (01): 31-37.
Su Shulan, Xue Ping, Ouyang Zhen, et al.Study on antiplatelet and antithrombin activitives and effective components variation of Puhuang-Wulingzhi before and after compatibility[J]. China Journal of Chinese Materia Medica, 2015, 40 (16): 3187-3193.
ZHANG Yue, DENG Hai-shan, SHI Le, et al. Study on the Intervention Effect of Shaofu Zhuyu Decoction on Blood Stasis Syndrome Based upon Non-target Plasma Metabolomics Strategy[J]. Journal of Nanjing University of Traditional Chinese Medicine, 2018, 34(03):318-321.
CHEN Zhuo. The Clinical Effect of Shaofu Zhuyu Decoction on Primary Dysmenorrhea of Cold Coagulation and Blood Stasis Type[J]. Asia-Pacific Traditional Medicine, 2019, 15(11):133-135.
LI Feng-jin, NIU Wen-ying, LIU Xin-xin, et al. Effect and Mechanism of Shaofu Zhuyutang on Endothelial Injury of Rats with Cold Coagulation and Blood Stasis Syndrome Based on Nrf2/ARE Signaling Pathway[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2021, 27(01):31-37.
Qiu Yuchang, Cao Ying, Kong Huanyu, et al. Experimental study on blood circulation and stasis activation as well as analgesic and anti-inflammatory effects of Shaohuayuyu Tang[J]. Chinese Journal of Traditional Medical Science and Technology, 2012, 19(06):498-499.
LU Ying, WU Tong, WU Jia-wen. Modified Shaofu Zhuyu Decoction inhibits TLR4/TRIF/IRF3 signaling pathway and improves inflammatory microenvironment in rats with endometriosis[J]. Progress of Anatomical Sciences, 2023, 29(05):483-486.
Meng Tongyu. Study on the intervention of Shaobuyu Tang plus and minus formula on cold-congealed blood stasis type dysmenorrhoea model rats[J]. Biped and Health, 2018, 27(06):181-182+184
WU Zengguang, HU Peng, FAN Baishuang, et al. Study on the effect of Shaofu Zhuyu Decoction on promoting blood circulation in rats with primary dysmenorrhea of cold-coagulating blood stasis syndrome[J]. Tianjin Journal of Traditional Chinese Medicine, 2020, 37 (08): 929-935.
GAO Hongjie, LI Jun, GONG Leilei. Research on Molecular Mechanism of Shaofu Zhuyu Decoction in the Treatment of Primary Dysmenorrhea Based on Integrated Pharmacology Platform V2.0[J]. Evaluation and Analysis of Drug-use in Hospitals of China, 2020, 20 (06): 682-684+688.
KONG Xiaojiao, LIU Jianhua, SONG Shuaihua, et al. Exploration of the Efficacy of ShaofuZhuyu Decoction with Addition and Reduction in the Treatment of Primary Dysmenorrhea with Cold Clotting and Blood Stasis[J]. Systems Medicine, 2023, 8 (03): 143-146.
Wu Xiuhong, Zhao Chuang, Yang Dongxia, et al. Study progress on pharmacological effects and clinical application of Shaofu Zhuyu Decoction[J]. Chinese Journal of Clinical Healthcare, 2017, 20(05):612-616.
Cong Xiao, Deng Chunxia. Effects of Shaofu Zhuyu Decoction in the Treatment of Primary Dysmenorrhea Patients on Estrogen, Prostaglandin E_2 and Clinical Efficacy[J]. World Chinese Medicine, 2018, 13(02):356-358+362.
Li Guoxin. Effects of shaofu Zhuyu Decoction on blood rheology, sex hormone levels and serum-related factors in patients with ovarian cysts with qi stagnation and blood stasis[J]. Strait Pharmaceutical Journal, 2020, 32(05):99-101.
YU Cong-hui, YANG Jie-yi. Effect of Shaofu Zhuyu Decoction on Hemodynamics, Sex Hormones and Serum Related Factors in Patients with Polycystic Ovary Syndrome[J]. Inner Mongolia Journal of Traditional Chinese Medicine, 2018, 37(10):11-13.
CHU Dongmei, LIU Rongxia, ZHANG Ying, et al. Clinical Effect of Shaofu Zhuyu Decoction on Chronic Pelvic Inflammation and Its Effect on Serum Immunoglobulin[J]. Chinese Archives of Traditional Chinese Medicine, 2022, 40(01):157-160.
Zhang Haiyan. Study on the effect of Shao Abdomen Evacuating Blood Stasis Soup together with Gui Zhi Fu Ling Soup in the treatment of chronic pelvic inflammatory disease and its effect on serum immunoglobulin[J]. Electronic Journal of Practical Gynecological Endocrinology, 2018, 5(03):57-58.
Ma Xiuling. Effect of Shaofu Zhuyu Decoction ultrasound ion implantation on chronic pelvic inflammation and its effects on hemorheology, intercellular cell adhesion molecule-1 and monocyte chemoattractant protein-1[J]. Journal of Practical Medical Techniques, 2020, 27(01):14-16.
Zheng Xiao-ting, Chen Sheng-hui, Yao Wen-liang, et al. A Review of Etiology and Pathogenesis of Chronic Prostatitis[J]. Modern Diagnosis and Treatment, 2019, 30 (11): 1810-1814.
SHAO Yaoning, LIANG Baojian, LIAO Guanghui. Clinical Study on Shaofu Zhuyu Tang for Chronic Prostatitis of Cold Congealing and Blood Stasis Type[J]. New Chinese Medicine, 2019, 51 (09): 68-70.
HAN Fu-qian, SHE Miao-hua, YUAN Kun-na, et al. Clinical Effect of Shaofu Zhuyu Decoction Combined with Acupuncture on Pain of Type Ⅲ Prostatitis[J]. Journal of Hebei Traditional Chinese Medicine and Pharmacology, 2021, 36 (06): 13-16+65.
Deng Guoyan, Xu Ruihao, Huge Jiletu, et al. Therapeutic effect observation of self-proposed qi-moving, blood-activating and anti-inflammatory formula in the treatment of qi stagnation and blood stasis type chronic prostatitis. [J]. Journal of Medicine and Pharmacy of Chinese Minorities, 2023, 29 (06): 7-9.
WANG Dinghai, TIAN Xiaoyan, WANG Xiaoyan, et al. Clinical observation on 87 cases of chronic prostatitis treated by Shaobastric Blood Stasis Expulsion Soup plus reduction with rectal drug administration[J]. Hunan Journal of Traditional Chinese Medicine, 2020, 36 (02): 50-52.
WANG Haohao, WANG Shizhen, ZHAO Qi, et al. Prof. Li Yueqing’s clinical experience in treating chronic prostatitis with the methods of warming and clearing[J]. Modern Chinese Clinical Medicine, 2022, 29 (04): 37-40.
YU Xudong, WANG Jisheng, DENG Sheng, et al. Professor LI Yueqing′s Clinical Experience in the Treatment of Prostate Disease[J]. World Chinese Medicine, 2021, 16 (15): 2342-2345.
SUN Song, LI Junbin, ZHAO Qi, et al. Professor Li Haisong's experience in treating male diseases by using Shaohuayouhuanyu Tang. [J]. Global Traditional Chinese Medicine, 2022, 15 (05): 815-817.
Yan Fenghua, Yan Xingke, He Tianyou. Progress of research on etiology and pathogenesis of chronic prostatitis[J]. Journal of Gansu College of Traditional Chinese Medicine, 2014, 31 (03): 98-101.
Yu Wenxiao. Multidisciplinary diagnosis and treatment guideline for benign prostatic hyperplasia with integrated Chinese and Western medicine (2022 edition) [J]. Chinese Journal of Andrology, 2022, 36 (02): 96-102.
GUAN Pengfei, LOU Hongkan, XU Xinyu, et al. Current status of research on traditional Chinese medicine in the treatment of benign prostatic hyperplasia[J]. Journal of Hubei Minzu University (Medical Edition), 2021, 38 (03): 69-72.
Cui Wenchen. Therapeutic effect observation of 46 patients with prostatic hyperplasia treated with combination of Chinese and Western medicine[J]. Contemporary Medicine, 2014, 12 (03): 307-308.
Nørby B, Røder A, Graugaard-Jensen C, Bliuckis R, Mikkelsen NT. Treatment of benign prostatic hyperplasia. Ugeskr Laeger. 2023, 185(14):312.
Liu Dongbo, Yin Deke. Analysis of the causes of complications after transurethral electrolysis of the prostate and progress of treatment[J]. CHINESE AND FOREIGN MEDICAL RESEARCH, 2019, 17 (01): 181-183.
ZHANG Shengjing, CHEN Tengfei, ZHAO Shengtian, et al. Prevention and Control Effect of Traditional Chinese Medicine on Complications after Transurethral Resection of Prostate[J]. GUANGMING JOURNAL OF CHINESE MEDICINE, 2021, 36 (21): 3599-360
GONG Xi-hao, DAI Heng-heng, WANG Ji-sheng, et al. Research Progress in Traditional Chinese and Western Medicine Treatment of Bladder Spasm after TURP[J]. World Journal of Integrated Traditional and Western Medicine, 2021, 16 (01): 192-196.
Chen Yin, Zheng Min, Tang Qunhui, et al. The Efficacy Analysis of Clyster with Chinese Medicine in Bladder Spastic Ache After Transurethral Resection of Prostate[J]. Chinese Archives of Traditional Chinese Medicine, 2010, 28 (08): 1691-1692.
Guo Hua. Therapeutic efficacy of tolterodine combined with Shaofu Zhuyu Decoction in the treatment of bladder spasm after prostatectomy [J]. Inner Mongolia Journal of Traditional Chinese Medicine, 2011, 30 (09): 68.
QIN Zhaojiang, ZHU Chengbin, ZHANG Kehui, et al. Experimental study on anti-prostatic hyperplasia in mice by Pu Huang granules[J]. Journal of Practical Traditional Chinese Medicine, 2017, 33 (09): 1004-1006.
ZHU Chengbin, QIN Zhaojiang, ZHANG Kehui, et al. Experimental study of Puhuang Dispensing Granule for the treatment benign prostate hyperplasia in mice model[J]. Laboratory Medicine and Clinic, 2018, 15 (18): 2705-2706+2710.
Huang Jian, Zhang Xuzhong. Guidelines for the diagnosis and treatment of urological and male diseases in China[M]. Beijing: Science Publishing House, 2022.
JIANG Deyou, WANG Lu, WANG Mengsi. Investigation on the Origin of Welling-abscess of the Testicle[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2019, 21 (12): 9-12.
TAO Fang-ze, CUI Yun, ZHOU Xiao-min, et al. Prof. Cui Yun's clinical experience in diagnosis and treatment of epididymitis[J]. Chinese Journal of General Practice, 2017, 15 (10): 1773-1775+1790.
Chen Xiao. Observation on the clinical efficacy of clinical treatment of chronic epididymitis (qi stagnation and blood stasis type) by combining the Shaofu Zhuyu Decoction[D]. Heilongjiang University of Traditional Chinese Medicine, 2022.
Yan Xiangli, Zhang Yan, Yuan Ye, et al. Overview of Professor Jia Liujin's application of Liumiao Tang in the treatment of damp-heat syndromes[J]. Lishizhen Medicine and Materia Medica Research, 2023, 34 (06): 1495-1497.
Li Hongjun, Hongkai, Li Zheng, et al. Guidelines for the treatment of male infertility[J]. National Journal of Andrology, 2022, 28 (01): 66-76.
Zhu Shaoming, Cheng Fan. A review: the mechanism of male sterility caused by varicocele[J]. Anhui Medical and Pharmaceutical Journal, 2017, 21(11):1945-1949.
ZHANG Luwei, Deng Zhiyuan, LI Xinping. Analysis of the law of treatment of varicocele in Chinese medicine[J]. Guiding Journal of Traditional Chinese Medicine and Pharmacy, 2019, 25(24):69-73.
CHEN Zhaohui, ZHANG Xinrong, LIU Qingyao, et al. Research progress of Chinese medicine in treating varicocele infertility of spermatic vein[J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2021, 30 (04): 448-452.
Sun Weiguo, Wang Jianfeng. Clinical Observation on the Therapy of Integrated Medicine in the Treatment of Varicocele for 30 Cases[J]. GUANGMING JOURNAL OF CHINESE MEDICINE, 2016, 31 (12): 1792-1794.
Wang Penglin. Treatment of 78 cases of varicocele combined with weak and oligozoospermia with the addition of Reducing Abdominal Blood Stasis Dispersion[J]. Henan Traditional Chinese Medicine, 2013, 33 (03): 403-404.
ZHU Yong, GE Xiaodong, LI Xiang, et al. Clinical study progress of Chinese medicine therapy for non-liquefaction of semen[J]. Chinese Journal of Human Sexuality, 2020, 29(07):103-106.
Tian Yuhe, Tian Qiao. Clinical observation of ShaofuZhuyu Decoction on semen liquefaction[J]. China Modern Medicine, 2010, 17(02):81-82.
Prevalence of, and Risk Factors for Erectile Dysfunction in Male Type 2 Diabetic Outpatient Attendees in Enugu, South East Nigeria [J]. Annals of African Medicine, 2018, 17 (4): 215-220.
WU Wenyan, GONG Guangming, LIU Lihong, et al. Pathogenesis of Diabetic Erectile Dysfunction in Traditional Chinese Medicine[J]. Journal of Practical Traditional Chinese Internal Medicine, 2023, 37(11):40-42.
JIA Xiaoyue, ZHANG Yujun, DUAN Yuhong, et al. Observation on the therapeutic effect of Shaofu Zhuyu Decoction combined with sildenafil on type 2 diabetic erectile dysfunction of syndrome of Qi Stagnation and blood stasis[J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2021, 30 (09): 931-935.
MAO Yinhui, WEI Zhitao, WANG Mingxing, et al. Discussion and experimental study of traditional Chinese medicine syndrome type in diabetic mellitus erectile dysfunction[J]. Chinese Journal of Human Sexuality, 2023, 32 (07): 125-129.
Ye H, Chen W, Cao P, Lin X, Zhang X, Xu F, Guo Q, Mao H, Yu X, Yang X. Prevalence of erectile dysfunction and its association with residual renal function in Chinese peritoneal dialysis patients. International and nephrology 2015 Feb;47(2):383-9.
HAN Meixiang, HUANG Yiqi, SHEN Weigang. Clinical Study on Shaofu Zhuyu Decoction Combined with Small-Dose Tadalafil for Erectile Dysfunction in Peritoneal Dialysis Patients[J]. New Chinese Medicine, 2023, 55(17):67-71.
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