Thoughts and Methods of Treating Precancerous Lesion of Gastric Cancer from the Perspectives of “Nutrient-Defense Regulation”

Abstract

The nutrient-defense emanates from the subtle qi of the spleen and stomach, which has nutritional and defensive functions. The gastric mucosa is an important place for digestion and can also defend against the invasion of foreign pathogens. Nutrient-defense and the gastric mucosa are similar in function. Exploring the etiology and pathogenesis of precancerous lesion of gastric cancer (PLGC) from the theory of “nutrient-defense regulation” and combines the physiological and pathological characteristics of the spleen and stomach. It is considered that the occurrence of PLGC is centered on the combination of toxin and blood stasis, and the deficiency of nutrient-defense and Qi-Yin is the key, thus resulting in corresponding pathological changes and clinical symptoms. Treatment should repair the gastric mucosal barrier and improve the clinical efficacy of PLGC by regulating nutrient-defense and balancing yin and yang.