Treating Lower Extremity Arteriosclerosis Obliterans from the Perspective of “Stasis”

Abstract

Lower extremity arteriosclerosis obliterans (ASO) is a chronic, progressive peripheral arterial disease characterized by atherosclerotic stenosis or occlusion, resulting in compromised blood supply to the lower extremities. Clinically, it presents with symptoms such as intermittent claudication, ischemic pain, decreased skin temperature, and, in advanced stages, ulceration and gangrene. Predominantly affecting middle-aged and elderly populations, the prevalence of ASO is escalating in tandem with global demographic aging trends. The disease significantly impairs patients’ quality of life, necessitating comprehensive and effective therapeutic strategies. Traditional Chinese Medicine (TCM) offers a unique and holistic approach to ASO management, with its emphasis on the concept of “blood stasis” (瘀血) as a central pathological mechanism. This paper elucidates the etiology, pathogenesis, and therapeutic interventions for ASO from the perspective of “stasis,” integrating classical TCM theories with contemporary clinical practices. By exploring the academic foundations, syndrome differentiation, treatment modalities, and preventive strategies, this study aims to provide novel insights and evidence-based approaches for the integrative management of ASO.