Epidemiological Analysis and Trend Forecast of Gynecological Diseases and Their Incidence by Age in China

Authors

  • Ruonan Zhao School of Public Health, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Rongrong Chen School of Public Health, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Xufei Zhao School of Public Health, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Lin Ma School of Public Health, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China
  • Rongqiang Zhang School of Public Health, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, China

DOI:

https://doi.org/10.53469/jcmp.2025.07(03).38

Keywords:

Gynecological diseases, Women, Disease burden

Abstract

Objective: To analyze the changes in the burden of gynecological diseases in China from 1990 to 2021 and the main types of gynecological diseases among women of different ages, providing a scientific basis for formulating prevention and treatment strategies for gynecological diseases. Methods: Absolute numbers and crude rates of incidence, mortality, and disability-adjusted life years (DALYs) for gynecological diseases among Chinese and global women from 1990 to 2021 were extracted from the 2021 Global Burden of Disease (GBD) database. Trends in the burden of disease and the main types of gynecological diseases among different age groups were analyzed. Results: In 2021, the number of new cases of gynecological diseases among Chinese women was 100.6675 million, with a standardized incidence rate of 14016.22 per 100,000, a decrease of 19.54% compared to 1990; the number of deaths from gynecological diseases among Chinese women in 2021 was 0.07 million cases, with a standardized mortality rate of 0.07 per 100,000, an increase of 57.14% compared to 1990; DALYs caused by gynecological diseases in China increased from 3.8283 million in 1990 to 3.9542 million in 2021. Conclusion: From 1990 to 2021, the number of global deaths, standardized mortality rates, and DALYs for gynecological diseases showed an overall upward trend, while standardized incidence rates and standardized DALY rates showed an overall downward trend. The situation for the prevention and treatment of gynecological diseases among Chinese women remains severe. It is essential to strengthen gynecological disease screening and prevention, especially in grassroots areas, improve women’s health education, and help them identify early symptoms and seek medical attention promptly. Additionally, increasing research investment, promoting the application of new technologies, and optimizing diagnostic and treatment methods are crucial to alleviating the burden of gynecological diseases and improving the quality of life for women.

References

Journal of Practical Gynecology and Obstetrics, 2022, 38(4): 4.

Ji N, Liu S W, Zeng X Y, et al. Study on the Disease Burden of Gynecolo Lang J H. Introduction to Women’s Health[J]. Chinese gical Diseases in China in 2016[J]. Chinese Journal of Obstetrics and Gynecology, 2018, 53(5): 313-318.

Germain A, Holmes K K, Piot P, et al. Reproductive tract infections; global impact and priorities for women’s reproductive health [J]. Plenum Press, 1992.

Ye H J. Survey and Analysis of the Current Status and Influencing Factors of Gynecological Diseases in the Shannan Region of Tibet[J]. Jilin University, 2016.

Li H, Qi M X, Guan X R. Trend of Disease Burden Changes in Gynecological Diseases in China from 1990 to 2019[J]. Modern Preventive Medicine, 2021, 48(18): 3322-3326, 3336. ISTIC PKU CA, 2021.

Yuan X W, Liu G H, Zhang W, et al. Survey and Analysis of Disease Characteristics in 3000 Cases of Gynecological Diseases in Adolescent Outpatients[J]. Chinese Journal of Sexual Science, 2020, 29(4): 3.

Gao Y Y, Liu C, Liu L C, et al. Analysis of the Influencing Factors of Gynecological Diseases in Rural Adult Women in Southwest Shandong Province in 2019[J]. Journal of Preventive Medicine and Information, 2021, 37(2): 9.

Wu C Z, Klebanoff J S, Tyan P, et al. Review of strategies and factors to maximize cost-effectiveness of robotic hysterectomies and myomectomies in benign gynecological disease [J]. Journal of Robotic Surgery, 2019.

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. (2024). Lancet, 403(10440), 1989-2056.

du Foss, Nadia A. Van der Hoorn, Marie-Louise P. van Lith, Jan M. M. le Cessie, SaskiaLashley, Eileen E. L. O. Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis [J]. Human reproduction update, 2020, 26(5).

Farren J, Mitchell-Jones N, Verbakel J Y, et al. The psychological impact of early pregnancy loss[J].Human reproduction update, 2018, 24(6):731-749.

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. (2024). Lancet, 403(10440), 2133-2161.

Horne, A. W., & Missmer, S. A. (2022). Pathophysiology, diagnosis, and management of endometriosis. Bmj, 379, e070750.

Taylor, H. S., Kotlyar, A. M., & Flores, V. A. (2021). Endometriosis is a chronic systemic disease: clinical challenges and novel innovations. Lancet, 397(10276), 839-852.

Della Corte, L., Di Filippo, C., Gabrielli, O., Reppuccia, S., La Rosa, V. L., Ragusa, R., ... Giampaolino, P. (2020). The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing. Int J Environ Res Public Health, 17(13).

Zondervan, K. T., Becker, C. M., Koga, K., Missmer, S. A., Taylor, R. N., & Viganò, P. (2018). Endometriosis. Nat Rev Dis Primers, 4(1), 9.

Terzic, M., Aimagambetova, G., Kunz, J., Bapayeva, G., Aitbayeva, B., Terzic, S., & Laganà, A. S. (2021). Molecular Basis of Endometriosis and Endometrial Cancer: Current Knowledge and Future Perspectives. Int J Mol Sci, 22(17).

Leone Roberti Maggiore, U., Bogani, G., Paolini, B., Martinelli, F., Chiarello, G., Spanò Bascio, L., ... Raspagliesi, F. (2024). Endometriosis-associated ovarian cancer: a different clinical entity. Int J Gynecol Cancer, 34(6), 863-870.

Kvaskoff, M., Mahamat-Saleh, Y., Farland, L. V., Shigesi, N., Terry, K. L., Harris, H. R., ... Missmer, S. A. (2021). Endometriosis and cancer: a systematic review and meta-analysis. Hum Reprod Update, 27(2), 393-420.

Onwude, J. L. (2012). Genital prolapse in women. BMJ Clin Evid, 2012.

Ali, M., Ciebiera, M., Vafaei, S., Alkhrait, S., Chen, H. Y., Chiang, Y. F., ... Al-Hendy, A. (2023). Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeutics. Cells, 12(8).

Alkhrait, S., Malasevskaia, I., & Madueke-Laveaux, O. S. (2023). Fibroids and Fertility. Obstet Gynecol Clin North Am, 50(4), 663-675.

Stewart, E. A., Cookson, C. L., Gandolfo, R. A., & Schulze-Rath, R. (2017). Epidemiology of uterine fibroids: a systematic review. Bjog, 124(10), 1501-1512.

Marsh, E. E., Al-Hendy, A., Kappus, D., Galitsky, A., Stewart, E. A., & Kerolous, M. (2018). Burden, Prevalence, and Treatment of Uterine Fibroids: A Survey of U.S. Women. J Womens Health (Larchmt), 27(11), 1359-1367.

Giuliani, E., As-Sanie, S., & Marsh, E. E. (2020). Epidemiology and management of uterine fibroids. Int J Gynaecol Obstet, 149(1), 3-9.

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Published

2025-03-28

How to Cite

Zhao, R., Chen, R., Zhao, X., Ma, L., & Zhang, R. (2025). Epidemiological Analysis and Trend Forecast of Gynecological Diseases and Their Incidence by Age in China. Journal of Contemporary Medical Practice, 7(3), 193–198. https://doi.org/10.53469/jcmp.2025.07(03).38