The Role and Mechanism of Various Cell Types in Myocardial Fibrosis
DOI:
https://doi.org/10.53469/jcmp.2025.07(03).22Keywords:
Myocardial fibrosis, Cardiomyocyte, Fibroblast, Myofibroblasts, Endothelial cellAbstract
Myocardial fibrosis is linked to the repair of myocardial injury and pathological ventricular remodeling. Various cell types, including fibroblasts, endothelial cells, cardiomyocytes, and immune cells, participate in the process of myocardial fibrosis through various mechanisms. However, there is a lack of effective targets for myocardial fibrosis. Thus, this review focuses on the effector cells for myocardial fibrosis and their potential mechanisms, which enhances the understanding of myocardial fibrosis and provides a theoretical foundation for its diagnosis and treatment.
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