Advances in Research on Astragalus and Cinnamon Twig Five-Substance Decoction for Qi Deficiency and Collateral Stasis Type Diabetic Peripheral Neuropathy
DOI:
https://doi.org/10.53469/jcmp.2025.07(03).16Keywords:
Diabetic peripheral neuropathy, Qi deficiency and collateral stasis, Astragalus and Cinnamon Twig Five-Substance Decoction, Clinical research, ReviewAbstract
Diabetic peripheral neuropathy (DPN) is one of the common complications of diabetes. The pain, numbness and sensory impairment caused by nerve damage are the main clinical manifestations, which seriously affect the quality of life of patients. According to traditional Chinese medicine, the pathogenesis of DPN is mainly qi deficiency, collaterals and blood stasis, and the basic principle should be invigorating qi, promoting blood circulation and dredging collaterals. As a classic prescription, Astragalus and Cinnamon Twig Five-Substance Decoction (ACTFSD) has remarkable effect in improving qi deficiency, collateral and blood stasis. In recent years, studies have shown that the decoction can effectively relieve the symptoms of diabetic peripheral neuropathy and improve the neurological function through multiple ways and multiple targets. This paper summarizes the research progress and action mechanism of DPN in the treatment of qi deficiency and collateral stasis, in order to provide reference for its clinical application and further research.
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Copyright (c) 2025 Xuemei Shang, Yanjin Su, Ying Zhang, Dong Gao, Jie Gao, Yongqiang Gao, Limin Jia
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