Effects of Vitamin D Deficiency on Oral Health

Authors

  • Okita Dan Odhiambo BDS 2nd Year, Inderprastha Dental College & Hospital

DOI:

https://doi.org/10.53469/jcmp.2024.06(11).53

Keywords:

Receptor, Teeth, Oral health, Enamel, Dentin, Bone, Hypomineralization, Guardian cell, Immunomodulation, Bone resorption, Bone density, Periodontal disease, Neurosteroid, Lactose intolerance, Skin pigmentation, Genetic polymorphism

Abstract

Vitamin D is a vital nutrient for human body. It is a fat - soluble secosteroid with a structure very similar to cholesterol. The Vitamin D receptor is a molecule that binds to the active form of Vitamin D2 and controls different processes, such as differentiation, inflammation, calcium and phosphorous absorption. Specifically, it’s main function is maintaining serum concentrations of calcium and phosphorous within normal ranges. Vitamin D can be synthesized in the skin, and it helps to facilitate intestinal calcium absorption. Ergosterol, which occurs in plants, is a vitamin D precursor. The active form of vitamin D is a steroid hormone. Renal activation of vitamin D is regulated by several endocrine factors. Liver and/or kidney disease can result in a 1, 25 (OH) 2D deficiency. Parathyroid hormone deficiency can be treated through vitamin D supplementation. Cholecalciferol rodenticide poisoning can cause symptoms of vitamin D toxicity. Glucocorticoids and calcitonin can be used to reverse symptoms of vitamin D toxicity. These days, people think that diet and lousy maintenance of teeth will affect their oral health and cause tooth decay. However, oral health can also be affected by our nutritional consumption. Any body part may be affected by vitamin D deficiency. Initial symptoms include muscle weakness, lower back pain, muscle aches, throbbing bone pain. When it comes to oral health, vitamin D deficiency may lead to tooth decay, tooth loss, bleeding gums, gingivitis, enamel erosion, hypomineralization. Thus vitamin D is an essential nutrient for our body. It is a kind of a vitamin which functions as steroid hormone which is mainly obtained from sunlight and dietary supplements as well.

References

Botelho J, Machado V, Proença L, Delgado A, Mendes J. Vitamin D Deficiency and Oral Health: A Comprehensive Review. Nutrients.2020; 12 (5): 1471.

Bener A, Hoffmann G, Al Darwish M. Vitamin D Deficiency and risk of dental caries among young children: A public health problem. Indian Journal of Oral Sciences.2013; 4 (2): 75.

Abdulmaguid R. Sherif S, Elsayed H. Assessment of Serum Vitamin D Levels in Young Adults and Correlation of Vitamin D Deficiency and Gingivitis. Egyptian Dental Journal.2017; 63 (3): 2413 - 2419.

Orbak R, Ozkan Y, Orbak Z. Dental manifestations of vitamin D deficiency in adolescents. Endocrine Abstracts.2019.

Ngangom A, Jain M, Verma S. Need of early dental intervention in vitamin D deficiency rickets. Indian Journal of Dental Sciences.2018: 10 (4): 229.

Khalaf RM, Almudhi AA. Effects of vitamin D deficiency on the rate of orthodontic tooth movement. An animal study. Saudi DentJ [Internet] 2022; 34 (2): 129 - 35.

Fulton A, Amlani M, Parekh S. Oral manifestations of vitamin D deficiency in children. Br Dent J [Internet] 2020: 228 (7): 515 - 8.

Swapna LA, Abdulsalam R. vitamin D Deficiency and its Effects on Tooth Structure and pulpal changes. Open Access Maced J Med Sci [Internet].2021: 9 (F): 81 - 7.

Xavier TA, Madalena IR, da Silva RAB, Silva MJB, De Rossi A, et al. vitamin D deficiency is a risk factor for delayed tooth eruption associated with persistent primary tooth. Acta Odontol Scand.2021: 79 (8): 600

- 5.

D’Ortenzio L, Kahlon B, Peacock T, Salhuddin H, Brickley M. The rachitic tooth: Refining the use of interglobular dentine in diagnosing vitamin D deficiency. Int J Paleopathol [Internet].2018: 22: 101 - 8.

Yogesh Hole et al 2019 J. Phys.: Conf. Ser.1362 012121.

Zihni Korkmaz M, Y emenoglu H, Günaçar DN, Ustaoglu G, Ates Yildirim E. The effects of vitamin D deficiency on mandibular bone.

Ramseier CA, Anerud A, Dulac M, Lulic M, Cullinan MP, Seymour GJ, et al. Natural history of periodontitis: Disease progression and tooth loss over 40 years. J Clin Periodontol.2017; 44 (12): 1182 - 91.

Botelho J, Machado V, Proenca L, Delgado AS, Mendes JJ. Vitamin D Deficiency and Oral Health: A Comprehensive Review. Nutrients.2020; 12 (5): 1471.

Holick MF, Binkley NC, Bischoff - Ferrari HA, Gordon CM, Hanley DA, Hanrey RP, et al. Evaluation, treatment, and prevention of Vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab.2011; 96 (7): 1911

- 30.

Dragonas P, El - Sioufi L, Bobetsis YA, Madianos PN. Association of Vitamin D with Periodontal Disease: A Narrative Review. Oral Health Prev Dent.2020; 18 (1): 103 - 14.

Olszewska - Czyz I, Firkova E. vitamin D3 Serum Levels in Periodontitis Patients: A Case - Control Study. Medicina (Kaunas).2022; 58 (5): 585.

Girgis E, Reyad AA. Vitamin D: Pharmacology and Clinical Challenges in Oral Health Care. J Int Acad Periodontol.2019; 21 (3): 118 - 24.

Machado V, Lobo S, Proenca L. Mendes JJ, Botelho

J. Vitamin D and Periodontitis: A Systematic Review and Meta - Analysis. Nutrients.2020; 12 (8): 2177.

Wells G, Shea B, O’Connell D, Peterson J, Welch V, LososM, et al. The Newcastle - Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta - analyses. Ottawa (Canada): The Ottawa Hospital [accessed April 2022].

Kuraner T, Beksac MS, Kayakirilmaz K, Caglayan F, Onderglu LS, Ozgunes H. Serum and parotid saliva testosterone, calcium, magnesium, and zinc levels in males, with and without periodontitis. Biol Trace Elem Res.1991; 31 (1): 43 - 9.

Acharya A, Kharadi MD, Dhavale R, Deshmukh VL, Sontakke AN. High salivary calcium level associated with periodontal disease in Indian subjects— a pilot study. Oral Health Prev Dent.2011; 9 (2): 195 - 200.

Antonoglou G, Knuuttila M, Niemela O, Hiltunen L, Raunio T, Karttunen R, et al. Serum 1, 25 (OH) D level increases after elimination of periodontal inflammation in TIDM subjects. J Clin Endocrinol Metab.2013; 98 (10): 3999 - 4005.

Millen AE, Andrews CA, LaMonte MJ, Hovey KM, Swanson M, Genco RJ, et al. Vitamin D status and 5 - year changes in periodontal disease measures among postmenopausal women: The Buffalo OsteoPerio Study. J Periodontol.2014; 85 (10): 1321 - 32.

Braegger C, Campoy C, Colomb V, Decsi T, Domellof M, Fewtrell M, et al. Vitamin D in the healthy european paediatric population. J Pediatr Gastroenterol Nutr.2013; 56: 692–701.

Munns CF, Shaw N, Kiely M, Specker BL, Thacher TD, Ozono K, et al. Global consensus recommendations on prevention and management of nutritional rickets. J Clin Endocrinol Metab.2016; 101: 394–415

Cashman KD. Vitamin D deficiency: defining, prevalence, causes, and strategies of addressing

Vos R, Ruttens D, Verleden SE, Vandermeulen E, Bellon H, Van Herck A, et al. High - dose vitamin D after lung transplantation: a randomized trial. J Heart Lung Transplant

Lee P, Nair P, Eisman JA, Center JR. Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality? Intensive care Med.2009; 35: 2028–32

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Published

2024-11-28

How to Cite

Odhiambo, O. D. (2024). Effects of Vitamin D Deficiency on Oral Health. Journal of Contemporary Medical Practice, 6(11), 269–271. https://doi.org/10.53469/jcmp.2024.06(11).53